性激素补充治疗在更年期女性保健中的效果分析  

Effect analysis of sex hormone replacement therapy in health care of climacteric women

作　　者：周伟慢 Zhou Weiman(Dingzhou City People’s Hospital in Hebei Province,Dingzhou 073000,China)

机构地区：[1]河北省定州市人民医院,河北定州073000

出　　处：《实用妇科内分泌电子杂志》2021年第23期64-66,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨性激素补充治疗在更年期女性保健治疗中的效果。方法选取2019年1月至2021年7月在定州市人民医院行更年期保健治疗的女性患者76例,随机分为观察组和对照组,每组38例。对照组采用常规保健治疗,观察组联合应用性激素补充治疗。比较两组治疗前后的性激素水平、更年期症状、焦虑与抑郁程度、生存质量、睡眠质量。结果治疗后,观察组促卵泡刺激素(FSH)、黄体生成素(LH)水平低于对照组,雌二醇(E_(2))水平高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组Kupperman评分为(10.16±5.35)分,低于对照组的(22.19±7.69)分,差异有统计学意义(P<0.05)。治疗后,观察组围绝经期生存质量量表(MENQOL)评分为(24.62±11.17)分,低于对照组的(47.69±13.52)分,差异有统计学意义(P<0.05)。治疗后,观察组焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组匹兹堡睡眠质量指数(PSQI)评分为(5.52±1.17)分,低于对照组的(10.06±1.22)分,差异有统计学意义(P<0.05)。结论性激素补充治疗有助于调节更年期女性的性激素水平,改善更年期症状,提高患者生存质量和治疗效果。Objective To explore the effect of sex hormone replacement therapy in the health care of climacteric women.Methods A total of 76 women with menopausal health care from January 2019 to July 2021 in the Dingzhou City People’s Hospital were randomly divided into observation group and control group,with 38 cases in each group.The control group was treated with routine health care,and the observation group was treated with additional sex hormone replacement therapy.The levels of sex hormones,menopausal symptoms,anxiety and depression,quality of life and quality of sleep were compared before and after treatment between the two groups.Results After treatment,the levels of follicle stimulating hormone(FSH)and luteinizing hormone(LH)in the observation group were significantly lower than those in the control group,while the level of estradiol(E_(2))was significantly higher than that in the control group(P<0.05).After treatment,the Kupperman score of the observation group was(10.16±5.35),which was significantly lower than(22.19±7.69)of the control group(P<0.05).After treatment,the score of the Menopause-specific Quality of Life Questionnaire(MENQOL)in the observation group was(24.62±11.17),which was significantly lower than(47.69±13.52)in the control group(P<0.05).After treatment,the scores of the Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)in the observation group were significantly lower than those in the control group(P<0.05).After treatment,the score of the Pittsburgh Sleep Quality Index(PSQI)in the observation group was(5.52±1.17),which was significantly lower than(10.06±1.22)in the control group(P<0.05).Conclusion Sex hormone replacement therapy is helpful to regulate the sex hormone level of climacteric women,improve menopausal symptoms,and improve the patient’s quality of life and therapeutic effect.

关 键 词：围绝经期综合征 性激素补充治疗 促卵泡刺激素 黄体生成素 雌二醇 围绝经期生存质量量表 匹兹堡睡眠质量指数 焦虑 抑郁 

分 类 号：R173[医药卫生—妇幼卫生保健]