超声中心肌做功参数的正常参考值范围及临床应用研究进展  

Research progress on normal reference value range and clinical applications of ultrasonic myocardial work parameters

作　　者：冯晓玄 冯颖青[2] FENG Xiaoxuan;FENG Yingqing(The Second School of Clinical Medicine,Southern Medical University,Guangzhou 510515,China;Guangdong Academy of Medical Sciences/Department of Cardiology,Guangdong Provincial People′s Hospital/Guangdong Cardiovascular Institute,Guangzhou 510080,China)

机构地区：[1]南方医科大学第二临床医学院,广东广州510515 [2]广东省医学科学院//广东省人民医院心内科//广东省心血管病研究所,广东广州510080

出　　处：《分子影像学杂志》2022年第6期957-966,共10页Journal of Molecular Imaging

基　　金：广东省重点领域研发计划项目(2019B020227005);广东省心血管系统疾病临床医学研究中心(2020B1111170011);广东省基础与应用基础研究基金项目(2020A1515010738)。

摘　　要：心肌做功(MW)技术通过结合二维斑点追踪超声心动图与无创肱动脉血压得到左室压力应变环,产生四个主要的参数评价心肌收缩功能。相比于目前临床上广泛应用的左室射血分数,MW在应变基础上具有更好地减少负荷对心肌功能评估的影响、提供整体与局部心肌功能信息和早期识别心血管疾病心肌功能受损情况等特点。本文首先介绍了MW原理及主要参数,归纳不同人群中MW参数正常参考值范围研究结果,对MW应用于临床心血管疾病心肌收缩功能评价的代表性研究成果做出综述,最后分析了MW的局限性,并对该技术良好的应用前景作出展望。Myocardial work(MW)technology obtains the left ventricular pressure-strain loop by combining two-dimensional speckle tracking echocardiography with noninvasive brachial artery blood pressure,and produces four main parameters to evaluate myocardial systolic function.Compared with the left ventricular ejection fraction,which is widely used in clinic at present,MW has the characteristics of better reducing the impact of load on the evaluation of myocardial function on the basis of strain,providing global and segmental myocardial function information,and early identifying the damage of myocardial function in cardiovascular diseases.This paper first introduces the principle and main parameters of MW,summarizes the research results of the normal reference value range of MW parameters in different populations,then the representative research results of MW applied to the evaluation of myocardial systolic function in clinical cardiovascular diseases are summarized,and finally analyzes the limitations of MW,as well as prospects the good application prospect of MW technology.

关 键 词：心肌做功技术 压力-应变环 正常参考值范围 人群研究 

分 类 号：R445.1[医药卫生—影像医学与核医学] R54[医药卫生—诊断学]