Ambivalent response in pathogen defense: A double-edged sword?  

作　　者：Chi-Yeol Kim Hyeunjeong Song Yong-Hwan Lee 

机构地区：[1]Department of Agricultural Biotechnology,Seoul National University,Seoul 08826,Korea [2]Plant Immunity Research Center,Seoul National University,Seoul 08826,Korea [3]Research Institute of Agriculture and Life Sciences,Seoul National University,Seoul 08826,Korea [4]Interdisciplinary Program in Agricultural Genomics,Seoul National University,Seoul 08826,Korea [5]Center for Fungal Genetic Resources,Seoul National University,Seoul 08826,Korea

出　　处：《Plant Communications》2022年第6期190-207,共18页植物通讯（英文）

基　　金：supported by grants from the National Research Foundation of Korea(NRF)(2018R1A5A1023599,2020R1A2B5B03096402,and 2021M3H9A1096935 to Y.-H.L.and 2019R1I1A1A01059802 to C.-Y.K.).C.-Y.K.is grateful for a graduate fellowship from the Brain Korea 21 Plus Program.

摘　　要：Plants possess effective immune systems that defend against most microbial attackers.Recent plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones in regulating the plant defense signaling network.Although most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems,newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel mechanisms.Here,we review the roles of both classical and more recently identified components of defense signaling pathways and stress hormones in regulating the ambivalence effect during responses to diverse pathogens.Because of their different lifestyles,effective defense against biotrophic pathogens normally leads to increased susceptibility to necrotrophs,and vice versa.Given these opposing forces,the plant potentially faces a trade-off when it mounts resistance to a specific pathogen,a phenomenon referred to here as the ambivalence effect.We also highlight a novel mechanism by which translational control of the proteins involved in the ambivalence effect can be used to engineer durable and broad-spectrum disease resistance,regardless of the lifestyle of the invading pathogen.

关 键 词：ambivalence effect crop protection hormone crosstalk PATHOGEN plant defense susceptibility(S)gene 

分 类 号：Q94[生物学—植物学]