Prolonged Viral Shedding in Three Young Adult Cases of COVID-19  

作　　者：Wen-Yi Dong Ming-Ju Zhou Lei Huang Chao Zhang Fu-Sheng Wang Zhou-Hua Xie 

机构地区：[1]Guangxi AIDS Clinical Treatment Centre,The Fourth People’s Hospital of Nanning,Nanning 530013,China [2]Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China [3]Medical Department of Infectious Diseases,The Fifth Medical Centre of Chinese PLA General Hospital,National Clinical Research Centre for Infectious Diseases,Beijing 100039,China

出　　处：《Infectious Diseases & Immunity》2022年第4期289-292,共4页感染性疾病与免疫（英文）

基　　金：supported by the Key Research and Development Program of Guangxi(AB20059001).

摘　　要：Severe acute respiratory syndrome coronavirus-2 infection is usually self-limited,with a short duration for viral shedding within several weeks.However,prolonged viral shedding has been observed in severe or immune-compromised coronavirus disease 2019(COVID-19)cases.Here,we reported that three young adult cases of COVID-19 patients,who were either immunosuppressed nor severe,showed prolonged viral RNA shedding from the upper respiratory tract for 58,81,and 137 days since initial diagnosis.To our knowledge,this is the longest duration of viral shedding reported to date in young adult patients.Further studies on factors relevant to prolonged viral positivity,as well as the correlation between viral positivity and transmission risk are needed for the optimal management of COVID-19 patients with prolonged nucleic acid positive.

关 键 词：COVID-19 Immune-competent Prolonged viral shedding SAR-CoV-2 

分 类 号：R563.1[医药卫生—呼吸系统]