核医学分子影像在胶质瘤诊疗中的研究进展  

Advances about molecular imaging of nuclear medicine in diagnosis and treatment of glioma

作　　者：徐洋 王凯[1] 陈嫱 艾林[1] Xu Yang;Wang Kai;Chen Qiang;Ai Lin(Department of nuclear medicine,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院核医学科,北京100070

出　　处：《首都医科大学学报》2022年第6期880-885,共6页Journal of Capital Medical University

基　　金：国家自然科学基金青年项目(82001769)。

摘　　要：胶质瘤是颅内最常见的肿瘤之一,患者预后通常较差。常规结构成像提供的信息有限,而分子影像尤其是核医学分子影像的快速发展为了解胶质瘤的生物学特性提供了独特的视角,能进一步增进医师对胶质瘤的理解。本文将对近年来核医学分子影像在胶质瘤诊断、分级、分子事件判断、疗效评估及患者预后预测等方面的研究进展进行综述。Glioma is one of the most common intracranial tumors,and the prognosis of patients is usually poor.Conventional structural imaging offers insufficient information,by contrast the rapid development of molecular imaging,especially molecular imaging of nuclear medicine,provides a unique perspective to understand the biological characteristics of glioma,and further enhances physicians understanding of glioma.This paper reviewed the advances of molecular imaging of nuclear medicine in the diagnosis,preoperative grading,judgment of molecular events,efficacy evaluation and prediction of prognosis of glioma in recent years.

关 键 词：分子影像 单光子发射型计算机断层显像(SPECT) 正电子发射型计算机断层显像(PET) 胶质瘤 

分 类 号：R445[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]