高通量血液透析法治疗对慢性肾衰竭尿毒症患者临床疗效、CRP、PCT及生活质量的影响  

Effects of High Flux Hemodialysis on Clinical Efficacy,CRP,PCT and Quality of Life of Uremic Patients with Chronic Renal Failure

作　　者：董彦荣 DONG Yanrong(Department of Hemodialysis Room,People's Hospital of Fengqiu County,Xinxiang Henan 453300,China)

机构地区：[1]封丘县人民医院血液透析室,河南新乡453300

出　　处：《临床研究》2022年第12期37-39,共3页Clinical Research

摘　　要：目的探讨高通量血液透析法(HFHD)治疗慢性肾衰竭(CRF)尿毒症患者对临床疗效、C反应蛋白(CRP)、降钙素原(PCT)及生活质量的影响。方法选取2020年3月至2022年3月封丘县人民医院收治的共计80例CRF尿毒症患者,按照随机摸球法分成治疗组(N=40)与对照组(N=40),对照组采用血液透析滤过治疗,治疗组采用HFHD治疗,对两组临床疗效、CRP、PCT水平及生活质量进行比较。结果治疗组(97.50%)治疗有效率与对照组(77.50%)相比更高,差异有统计学意义(P<0.05);治疗后两组CRP、PCT水平降低,差异有统计学意义(P<0.05),治疗组水平与对照组相比更低,差异有统计学意义(P<0.05);两组治疗后生活质量综合评定问卷(GQOLI-74)量表评分提高,差异有统计学意义(P<0.05),治疗组评分与对照组相比更高,差异有统计学意义(P<0.05)。结论HFHD应用于CRF尿毒症患者治疗中,可提高临床疗效,改善CRP、PCT水平,提高生活质量。Objective To explore the effect of high flux hemodialysis(HFHD)on clinical efficacy,C-reactive protein(CRP),procalcitonin(PCT)and quality of life in uremic patients with chronic renal failure(CRF).Methods A total of 80 patients with CRF uremia who were admitted in Fengqiu County People's Hospital from March 2020 to March 2022 were selected,and divided into the treatment group(N=40)and the control group(N=40)by random touching ball method.The control group was treated with hemodialysis filtration,and the treatment group was treated with HFHD.The clinical efficacy,CRP,PCT levels,and quality of life of the two groups were compared.Results Compared with the control group(77.50%),the total effective rate of the treatment group(97.50%)was higher,with significant difference(P<0.05).After treatment,the levels of CRP and PCT in the two groups were decreased,with significant differences(P<0.05),and compared with the control group,the levels in the treatment group were lower,with significant differences(P<0.05).After treatment,the scores of the comprehensive quality of life assessment questionnaire(GQOLI-74)in the two groups were improved,with significant differences(P<0.05),and compared with the control group,the scores in the treatment group were higher,with significant differences(P<0.05).Conclusion HFHD treatment can improve the clinical efficacy,the level of CRP and PCT,and the quality of life with CRF uremia patients.

关 键 词：高通量血液透析法 慢性肾衰竭尿毒症 C反应蛋白 降钙素原 生活质量 

分 类 号：R692.5[医药卫生—泌尿科学]