去氢枞酸基丙二胺席夫碱衍生物的合成与表征  

Synthesis and Characterization of Hydroabietic Acid Propylene Diamine Schiff Base Derivatives

作　　者：韦有杰 黄志聪 庄兰雄 甘永乐 Wei Youjie;Huang Zhicong;Zhuang Lanxiong;Gan Yongle(College of Preparatory Education,Baise University,Baise 533000,China;College of Chemistry&Environment Engingeering,Baise University,Baise 533000,China)

机构地区：[1]百色学院预科教育学院,广西百色533000 [2]百色学院化学与环境工程学院,广西百色533000

出　　处：《山东化工》2022年第20期35-36,39,共3页Shandong Chemical Industry

基　　金：广西教育厅2020年度广西高校中青年教师科研基础能力提升项目(NO:2020KY19016)。

摘　　要：去氢枞酸是一种具有多个手性中心的二萜类化合物,本身具多种生物活性。本文以去氢枞酸为原料,先经SOCl_(2)酰氯化得到去氢枞酸酰氯,再与用1,3-丙二胺与取代苯甲醛反应得到的取代苯甲醛缩1,3-丙二胺单席夫碱化合。最后得到去氢枞酸基丙二胺席夫碱衍生物,通过IR及^(1)HNMR等手段对目标化合物进行了结构表征。Dehydroabietic acid is a kind of diterpenoid compound with multiple chiral centers,which has a variety of biological activities.In this paper,dehydroabietic acid was used as raw material to obtain dehydroabietic acid chloride by chlorination of SOCl_(2).Substituted benzaldehyde 1,3-propylene diamine single Schiff base was obtained by reaction of substituted benzaldehyde with 1,3-propylene diamine.At last,dehydroabietylglyceryl chloride was reacted with Schiff base to obtain dehydroabietyl propylene diamine Schiff base derivative.The structures of the target compounds were characterized by IR and ^(1)H NMR.

关 键 词：去氢枞酸 席夫碱 合成 表征 

分 类 号：TQ201[化学工程—有机化工] O626.32[理学—有机化学]