阻塞性睡眠呼吸暂停与脑小血管病关系研究进展  

Obstructive sleep apnea hypopnea syndrome and cerebral small vessel diseases

作　　者：史晓英 何洪真 许静[2] 徐国栋[2] 董艳红[2] 吕佩源[2] Shi Xiaoying;He Hongzhen;Xu Jing;Xu Guodong;Dong Yanhong;Lyu Peiyuan(Graduate School of Hebei Medical University,Shijiazhuang 050017,China;不详)

机构地区：[1]河北医科大学研究生学院,石家庄050017 [2]河北省人民医院神经内科

出　　处：《中国脑血管病杂志》2022年第11期783-787,共5页Chinese Journal of Cerebrovascular Diseases

基　　金：科技创新2030——重大项目(2021ZD0201807);2019年河北省政府资助临床医学优秀人才培养项目(冀财社[2019]139号);2020年河北省高端人才支持计划(冀办[2019]63号)。

摘　　要：阻塞性睡眠呼吸暂停(OSA)是常见的临床慢性多系统受累疾病,可引起中枢神经、心脑血管、内分泌及呼吸等多系统的损害。OSA与脑小血管病的发生发展密切相关,该文就OSA与脑小血管病血液学及影像学标志物、脑血流、脑结构、脑网络及认知功能之间的关系进行综述。Obstructive sleep apnea hypopnea syndrome(OSA) is a common clinical chronic multi-system disease, which can cause damage to the central nervous system, cardiovascular system, endocrine system and respiratory system. Studies have shown that OSA is closely related to the occurrence and development of cerebral small vessel diseases(CSVD). This paper reviewed the relationship between OSA and CSVD hematological and imaging markers, cerebral blood flow, brain structure, brain network and cognitive function.

关 键 词：睡眠呼吸暂停 阻塞性 脑小血管病 脑血流 脑结构 认知 综述 

分 类 号：R766[医药卫生—耳鼻咽喉科] R743[医药卫生—临床医学]