中医药调节肠道菌群治疗慢传输型便秘的研究进展  

Research progress of traditional Chinese medicine regulating intestinal flora in the treatment of slow transit constipation

作　　者：施敏 刘富林 夏旭婷 廖陈敏 SHI Min;LIU Fulin;XIA Xuting;LIAO Chenmin(Chinese Medicine College,Hunan University of Chinese Medicine,Hunan Province,Changsha 410208,China)

机构地区：[1]湖南中医药大学中医学院,湖南长沙410208

出　　处：《中国医药导报》2022年第32期47-50,共4页China Medical Herald

基　　金：国家自然科学基金青年科学基金项目(81603597);湖南省教育厅优秀青年项目(19B424);湖南省中医药科研计划项目(201954)。

摘　　要：本文基于肠道菌群与慢传输型便秘之间的关系,探讨了中医药调节肠道菌群治疗该病的机制,认为肠道菌群的生理功能与传统医学的整体观念及阴阳平衡理论契合。慢传输型便秘的发病与肠道菌群失调有关,中医药可以通过调节肠道菌群代谢产物、肠道神经递质、肠道免疫应答等途径促进胃肠动力提升,从而改善慢传输型便秘。本文揭示了中医药调节肠道菌群治疗慢传输型便秘的作用机制,为中医药在防治该疾病的临床与科研提供理论参考。Based on the relationship between intestinal flora and slow transit constipation,this paper discusses the mechanism of traditional Chinese medicine regulating intestinal flora in the treatment of this disease,and believes that the physiological function of intestinal flora is consistent with the holism of traditional medicine and the theory of yin and yang balance.The onset of slow transit constipation is related to intestinal flora imbalance.Traditional Chinese medicine can promote gastrointestinal motility by regulating metabolites of intestinal flora,intestinal neurotransmitters,and intestinal immune response,so as to improve slow transit constipation.This paper reveals the mechanism of traditional Chinese medicine regulating intestinal flora in the treatment of slow transit constipation,and provides theoretical reference for the clinical and scientific research of traditional Chinese medicine in the prevention and treatment of this disease.

关 键 词：中医药 肠道菌群 肠道神经递质 慢传输型便秘 

分 类 号：R256.3[医药卫生—中医内科学]