血脂水平和血脂综合指数与儿童喘息性疾病的相关性分析  

Relationship analysis of serum lipid level and lipid combine index with wheezing diseases in children

作　　者：赵逸东 姚嘉琦 赵轩 桂晶晶 朱琳杰 金阿全 张力文 黄志英 ZHAO Yidong;YAO Jiaqi;ZHAO Xuan;GUI Jingjing;ZHU Linjie;JIN Aquan;ZHANG Liwen;HUANG Zhiying(Department of Pediatrics,Changzhou Second People’s Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Changzhou 213000,China)

机构地区：[1]南京医科大学附属常州第二人民医院儿科,江苏常州213000

出　　处：《中国医药导报》2022年第32期92-95,共4页China Medical Herald

基　　金：江苏省卫生健康委员会基金资助项目(H2018010)。

摘　　要：目的探讨儿童血脂水平和血脂综合指数(LCI)与儿童喘息性疾病的相关性。方法选择2016年7月至2021年6月南京医科大学附属常州市第二人民医院儿科住院并行血脂分析检查6311例患儿,据患儿入院时是否有喘息症状或体征分为喘息组(1707例)及非喘息组(4604例),同时根据体重指数(BMI)将其分为超重肥胖喘息组(466例)和超重肥胖非喘息组(722例)。收集患儿的一般资料及血脂指标,计算LCI;分析血脂水平和LCI与儿童喘息性疾病的相关性。结果喘息组与非喘息组性别、年龄、BMI、既往气喘史、单纯母乳喂养、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇(HDL-C)及LCI比较,差异有统计学意义(P<0.05)。性别、年龄、BMI、既往气喘史及TC是儿童喘息性疾病的影响因素(P<0.05)。超重肥胖喘息组与非喘息组性别、年龄、BMI、既往气喘史、TC、TG、HDL-C及LCI比较,差异有统计学意义(P<0.05)。性别、年龄、既往有气喘史、TC、TG及LCI是超重肥胖患儿喘息性疾病发生的影响因素(P<0.05)。结论血脂水平和LCI与儿童喘息有关,与LCI无关。Objective To explore the relationship of serum lipid level and lipid combine index(LCI)with wheezing diseases in children.Methods A total of 6311 children hospitalized in the Department of Pediatrics,Changzhou Second People’s Hospital Affiliated to Nanjing Medical University from July 2016 to June 2021 were selected for blood lipid analysis.The children were divided into wheezing group(1707 cases)and non-wheezing group(4604 cases)according to whether they had wheezing symptoms or signs at admission;according to body mass index(BMI),the children were divided into overweight-obese wheezing group(466 cases)and overweight-obese non-wheezing group(722 cases).The general data and blood lipid indexes of the children were collected,and LCI was calculated;the correlation between serum lipid level,LCI and asthmatic diseases in children were analyzed.Results There were significant differences in gender,age,BMI,previous history of asthma,breastfeeding alone,total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol,high density lipoprotein cholesterol(HDL-C),and LCI between wheezing group and non-wheezing group(P<0.05).Gender,age,BMI,previous history of asthma,and TC were the influencing factors of asthmatic diseases in children(P<0.05).There were significant differences in gender,age,BMI,previous history of asthma,TC,TG,HDL-C,and LCI between overweight-obese wheezing group and overweight-obese non-wheezing group(P<0.05).Gender,age,previous history of asthma,TC,TG,and LCI were the influencing factors of asthmatic diseases in overweight-obese children(P<0.05).Conclusion Lipid levels is associated with wheezing in children,but not with LCI.

关 键 词：血脂 血脂综合指数 儿童 喘息性疾病 

分 类 号：R725.6[医药卫生—儿科]