桑杞清眩颗粒治疗高血压患者的临床特点及中医证素分布  

Clinical characteristics and distribution of traditional Chinese medicine syndrome elements of Sangqi Qingxuan Granules in treating hypertension

作　　者：任卫全 樊佳溶 张高钰 何清 廖江铨[3] 黄力[3] 李琳[3] REN Weiquan;FAN Jiarong;ZHANG Gaoyu;HE Qing;LIAO Jiangquan;HUANG Li;LI Lin(Department of Traditional Chinese Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Beijing University of Chinese Medicine,Beijing 100029,China;Department of Cardiology of Integrated Chinese and Western Medicine,China-Japan Friendship Hospital,Beijing 100029,China)

机构地区：[1]首都医科大学宣武医院中医科,北京100053 [2]北京中医药大学,北京100029 [3]中日友好医院中西医结合心内科,北京100029

出　　处：《中国医药导报》2022年第32期117-121,共5页China Medical Herald

基　　金：国家自然科学基金青年科学基金项目(81803923);首都卫生发展科研专项项目(2018-2-4063)。

摘　　要：目的评价桑杞清眩颗治疗高血压患者的临床特点及证素分布。方法选取中日友好医院2018年1月至2019年12月黄力教授开处桑杞清眩颗粒的150名高血压患者进行临床一般资料和证素评价的收集,观察患者症状、舌脉、证素等分布情况。结果问卷共发放150份,共回收有效问卷122份。人群性别分布以男性偏多(62例,占50.8%),年龄分布以<60岁患者居多(78例,63.93%),体重肥胖者较多(54例,占44.26%),高血压分级以1级多见(74例,占60.66%);中医证候方面,头晕、头疼、眠差、梦多和便干为最常见症状,患者以淡红舌、薄苔,脉弦细、阳亢证居多。聚类分析所呈现的证素组合规律分为3种:阳亢;阴虚;血瘀、气虚、气滞、痰、湿、热。结论桑杞清眩颗粒治疗1级高血压效果突出,尤其适用于中医辨证为肝肾阴虚、肝阳上亢证的患者。Objective To evaluate the clinical characteristics and distribution of traditional Chinese medicine syndrome elements of patients with hypertension treated by Sangqi Qingxuan Granules.Methods From January 2018 to December 2019,a total of 150 hypertensive patients who were treated with Sangqi Qingxuan Granules by Professor Huang Li in China-Japan Friendship Hospital were selected for the collection of clinical general data and syndrome element evaluation.The distribution of symptoms,tongue and pulse,syndrome elements were observed.Results A total of 150 questionnaires were distributed and 122 valid questionnaires were collected.The gender distribution of the population was mostly male(62 cases,accounting for 50.8%),the age distribution was mostly patients under 60 years old(78 cases,63.93%),the body weight was more obese(54 cases,accounting for 44.26%),and the hypertension grade was more common in grade 1(74 cases,accounting for 60.66%).In terms of traditional Chinese medicine syndromes,dizziness,headache,poor sleep,more dreams and dry stools were the most common symptoms.The patients were mostly characterized by pink tongue,thin fur,stringy and thready pulse,and syndrome of hyperactivity of yang.Cluster analysis showed three patterns of combination of syndrome elements:hyperactivity of yang;yin deficiency;blood stasis,qi deficiency,qi stagnation,phlegm,dampness,heat.Conclusion Sangqi Qingxuan Granules is effective in the treatment of grade 1 hypertension,especially for patients with syndrome of yin deficiency of liver and kidney and syndrome of upper hyperactivity of liver yang.

关 键 词：桑杞清眩颗粒 高血压 中医证素 肝阳上亢 

分 类 号：R259[医药卫生—中西医结合]