白背叶楤木化学成分研究  

Chemical constituents from Aralia chinensis var. nuda

作　　者：尹芃程 王亭 钱海珊 李绍花 李红芳 李艳平 何红平 李宝晶 YIN Peng-cheng;WANG Ting;QIAN Hai-shan;LI Shao-hua;LI Hong-fang;LI Yan-ping;HE Hong-ping;LI Bao-jing(College of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China;Yunnan Key Laboratory of Dai and Yi Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China)

机构地区：[1]云南中医药大学中药学院,云南昆明650500 [2]云南中医药大学云南省傣医药与彝医药重点实验室,云南昆明650500

出　　处：《中成药》2022年第11期3522-3525,共4页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金(81860760,81760745);云南省应用基础研究计划(2019FB117);云南省应用基础研究计划中医联合专项[2018FF001(-024),202001AZ070001-044,202101AZ070001-159];云南省重大项目专项(202002AA100007)。

摘　　要：目的 研究白背叶楤木Aralia chinensis Linn. var.nuda Nakai化学成分。方法 白背叶楤木70%乙醇提取物经过硅胶、ODS、Sephadex LH-20柱色谱及HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果 从中分离得到11个化合物,分别鉴定为对羟基苯丙酸乙酯(1)、顺式对羟基肉桂酸乙酯(2)、反式对羟基肉桂酸乙酯(3)、咖啡酸(4)、6, 7-二羟基香豆素(5)、3, 4-二羟基苯甲酸(6)、槲皮素(7)、山柰酚(8)、异槲皮苷(9)、二十八烷醇(10)、十六烷酸(11)。结论 化合物1~11均为首次从该植物中分离得到,化合物1~3、6、9、10为首次从楤木属植物中分离得到。AIM To study the chemical constituents of Aralia chinensis Linn. var. nuda Nakai.METHODS The 70% ethanol extract from A. chinensis var. nuda was isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatography and HPLC, then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESLUTS Eleven compounds were isolated and identified as ethyl 4-hydroxyhydrocinnamate(1), cis-p-hydroxyl ethyl cinnamate(2), trans-p-hydroxyl ethyl cinnamate(3), caffeic acid(4), 6, 7-dihydroxycoumarin(5), 3, 4-dihydroxybenzoic acid(6), quercetin(7), kaempferol(8), isoquercitrin(9), octacosanol(10), palmitic acid(11).CONCLUSION Compounds 1-11 are isolated from this plant for the first time, and compounds 1-3, 6, 9, 10 are isolated from this genus Aralia for the first time.

关 键 词：白背叶楤木 化学成分 分离鉴定 

分 类 号：R284.1[医药卫生—中药学]