Perspectives on diagnosis and surgical treatment of congenital cervical malformations  

先天性子宫颈发育不良的诊断及手术治疗

作　　者：Yiying Sun Grigoris F.Grimbizis Lan Zhu 孙祎赢;Grigoris F.Grimbizis;朱兰(Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100032,China;1st Department of Obstetrics and Gynecology,Medical Faculty,Aristotle University of Thessaloniki,Papageorgiou General Hospital,Thessaloniki 56403,Greece)

机构地区：[1]Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100032,China [2]1st Department of Obstetrics and Gynecology,Medical Faculty,Aristotle University of Thessaloniki,Papageorgiou General Hospital,Thessaloniki 56403,Greece

出　　处：《Science Bulletin》2022年第19期1935-1938,共4页科学通报（英文版）

基　　金：supported by the National Key Research and Development Program of China(2021YFC2701401);the National Natural Science Foundation of China(82171614);the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences(2020-PT320-003 and 2021-PT320-001)。

摘　　要：Malformations of the female lower genital tract are congenital deviations from normal anatomy caused by abnormal development of the Müllerian ducts and urogenital sinus.These malformations may cause troublesome symptoms in adolescent girls after puberty and have substantially negative impact on their reproductive potential and mental health.Congenital cervical malformations(CCMs)are the most challenging and complicated entity in this territory.They are caused by abnormal bilateral Mullerian fusion and later canalization,manifested by the absence or underdevelopment of the cervix,leading to the obstruction of the cervical canal for evacuation of menses at menarche.Their prevalence ranges from 1/80,000 to 1/100,000[1],and approximately half of patients coexist with congenital vaginal agenesis[2].

关 键 词：ANATOMY CONGENITAL CERVICAL 

分 类 号：R713.4[医药卫生—妇产科学]