静脉超声造影在评估子宫腺肌症GnRH-a治疗疗效的应用价值  

Value of Intravenous Contrast enhanced Ultrasound used to observe the efficacy and analysis of GnRH agonist in adenomyosis

作　　者：黄如甸 廖莉婷 覃美英[1] 农花艳 刘梅[1] Huang Rudian;Liao Liting;Tan Meiying;Nong Huayan;Liu Mei(Department of Obstetrics and Gynecology,Qinzhou first people's Hospital,Guangxi Qinzhou 535000,China)

机构地区：[1]钦州市第一人民医院妇产科,广西钦州535000

出　　处：《实用妇科内分泌电子杂志》2022年第8期97-100,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨静脉超声造影在子宫腺肌症GnRH-a治疗疗效评估中的临床应用价值。方法对于2020年7月至2021年10月在本院接受GnRH-a治疗的80例子宫腺肌症患者,随机分为两组,每组40例,观察组采用静脉超声造影评估疗效,而对照组采用阴道超声检查评估其疗效。通过子宫腺肌症GnRH-a治疗前及治疗后3个月病灶的微循环血流灌注情况、病灶位置、范围、内膜回声情况及子宫体积大小,通过计算病灶及子宫体积、子宫内膜厚度、评估痛经VAS评分及经量PBAC评分评估疗效,比较两组对疗效的评价。结果治疗前,两组子宫体积、病灶体积、痛经VAS评分、子宫内膜厚度及经量PBAC评分比较,差异无统计学意义(P>0.05);治疗后3个月,观察组子宫体积、病灶体积小于对照组,痛经VAS评分低于对照组,子宫内膜厚度薄于对照组,经量PBAC评分低于对照组,差异具有统计学意义(P<0.05)。观察组病灶内微循环血流灌注检出率65.0%高于对照组的37.5%,差异具有统计学意义(P<0.05)。结论GnRH-a治疗子宫腺肌症疗效显著,运用静脉超声造影可有效评价GnRH-a治疗子宫腺肌症的疗效。Objective To explore the clinical value of intravenous contrast-enhanced ultrasound in the evaluation of the therapeutic effect of GnRH-a in adenomyosis.Methods 80 patients with adenomyosis treated with GnRH-a in our hospital from July 2020 to October 2021 were randomly divided into two groups,with 40 people in each group.The curative effect was evaluated by intravenous contrast-enhanced ultrasonography in the observation group and transvaginal ultrasonography in the control group.Through the microcirculation blood flow perfusion,location,range,endometrial echo and uterine volume of the focus before and 3 months after treatment of adenomyosis GnRH-a,the curative effect was evaluated by calculating the focus and uterine volume,endometrial thickness,dysmenorrhea vas score and menstrual PBAC score,and the evaluation of the curative effect between the two groups was compared.Results Before treatment,there were no significant differences in uterine volume,lesion volume,dysmenorrhea VAS score,endometrial thickness and menstrual volume PBAC score between the two groups(P>0.05).At 3 months after treatment,the uterine volume and lesion volume in the observation group were lower than those in the control group,the dysmenorrhea VAS score,endometrial thickness and menstrual volume PBAC were lower than those in the control group,and the differences were statistically significant(P<0.05).The detection rate of microcirculation blood perfusion in the observation group was 65.0%higher than that in the control group(37.5%),the difference was statistically significant(P<0.05).Conclusion GnRH-a is effective in the treatment of adenomyosis.Intravenous contrast-enhanced ultrasonography can effectively evaluate the efficacy of GnRH-a in the treatment of adenomyosis.

关 键 词：超声造影 子宫腺肌症 GNRH-A 

分 类 号：R711.74[医药卫生—妇产科学]