原发性醛固酮增多症诊断中CXCR4受体显像的临床应用专家共识(2022)  

Consensus on Clinical Application of the CXCR4-targeted Imaging in the Diagnosis of Primary Aldosteronism(2022)

作　　者：中国医师协会泌尿外科医师分会肾上腺性高血压外科协作组 中华医学会内分泌学分会肾上腺学组 中华医学会核医学分会PET学组 张玉石[2] 童安莉[3] 霍力[4] 丁洁 郑国洋[6] 高寅洁 Chinese Urological Doctor Association Adrenal Hypertension Surgery Collaborative Organization Adrenal Group;Chinese Society of Endocrinology PET group;Chinese Society of Nuclear Medicine;ZHANG Yushi;TONG Anli;HUO Li(不详;Department of Urology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Nuclear Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]不详 [2]中国医学科学院北京协和医院泌尿外科,北京100730 [3]中国医学科学院北京协和医院内分泌科,北京100730 [4]中国医学科学院北京协和医院核医学科,北京100730 [5]北京协和医院核医学科 [6]北京协和医院泌尿外科 [7]北京协和医院内分泌科

出　　处：《协和医学杂志》2022年第6期986-991,共6页Medical Journal of Peking Union Medical College Hospital

基　　金：中央高水平医院临床科研业务费(2022-PUMCH-C-028,2022-PUMCH-B-010);中国医学科学院创新工程(2022-I2M-JB-001)。

摘　　要：原发性醛固酮增多症的分型诊断是临床工作的重点和难点,越来越多的临床证据表明,靶向CXCR4的^(68)Ga-Pentixafor PET/CT核素显像可辅助原发性醛固酮增多症的分型。基于国内外最新研究证据,经多学科专家组深入讨论,在核素显像方法和结果判读,以及其对治疗方案的指导和预后评估方面达成了一致意见。本共识为规范国内^(68)Ga-Pentixafor PET/CT显像,提高我国原发性醛固酮增多症诊疗水平提供了重要依据。Subtype classification of primary aldosteronism is important but challenging.Increasing evidence has shown that^(68)Ga-Pentixafor PET/CT imaging which targets CXCR4 is beneficial to the subtype classification of primary aldosteronism.Based on all the available evidence,and after in-depth discussion of a group of multi-disciplinary experts,a consensus has been established,which covers imaging technology,interpretation of results of CXCR4 imaging,and the guidance to the choice of the treatment and prognosisevaluation.The consensus is helpful for standardizing^(68)Ga-Pentixafor PET/CT imaging and promoting a better diagnosis procedure in primary aldosteronism.

关 键 词：原发性醛固酮增多症 CXCR4受体 ^(68)Ga-Pentixafor PET/CT 专家共识 

分 类 号：R586.24[医药卫生—内分泌]