先天性肛门直肠畸形患儿术后排尿异常相关因素分析  

Risk factors of postoperative voiding dysfunction in children with congenital anorectal malformation

作　　者：贾茹 宋翠萍[1] 窦启锋[1] 张会清[1] 文建国[2] Jia Ru;Song Cuiping;Dou Qifeng;Zhang Huiqing;Wen Jianguo(Pediatric surgery,the First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,China;Department of Urology,First Affiliated Hospital of Zhengzhou University,Henan Joint International Pediatric Urodynamic Laboratory,Zhengzhou 450052,China)

机构地区：[1]新乡医学院第一附属医院小儿外科,新乡453100 [2]郑州大学第一附属医院泌尿外科河南省小儿尿动力国际联合实验室,郑州450052

出　　处：《中华医学杂志》2022年第38期3033-3036,共4页National Medical Journal of China

基　　金：国家自然科学基金(U1904208);河南省医学科技攻关计划省部共建项目(SBGJ2018059)。

摘　　要：本研究分析2006年至2021年手术治疗的先天性肛门直肠畸形(ARM)患儿的临床资料,探讨ARM患儿术后排尿异常的相关因素。共纳入患儿60例,其中男51例、女9例,年龄4~15岁。其中,43例排尿正常,17例排尿异常。通过尿动力学检查随访发现中-高位临床分型(OR=6.732,95%CI:1.854~24.443)、多次手术(OR=3.712,95%CI:1.133~12.160)、合并脊柱畸形(OR=3.297,95%CI:1.029~10.566)和术后排便异常(OR=4.971,95%CI:1.387~17.816)是ARM术后排尿异常的危险因素(均P<0.05)。因此ARM术后患儿应进行尿动力学随访并给予早期干预治疗。This study analyzed the clinical data of children with anorectal malformation(ARM)who underwent surgery from 2006 to 2021,and explored the related factors of postoperative voiding dysfunction(VD).A total of 60 children including 51 males and 9 females,aged 4-15 years,were enrolled.During follow up,normal voiding function were found in 43 cases,VD in 17 cases.It was found that middle to high clinical classification(OR=6.732,95%CI:1.854-24.443),multiple surgeries(OR=3.712,95%CI:1.133-12.160),associated spinal deformity(OR=3.297,95%CI:1.029-10.566)and abnormal postoperative defecation(OR=4.971,95%CI:1.387-17.816)were the risk factors of VD after ARM(all P<0.05).Urodynamic study and early intervention should be carried out in children with VD after ARM surgery.

关 键 词：儿童 先天性肛门直肠畸形 排尿异常 尿动力检查 危险因素 横断面研究 

分 类 号：R726.5[医药卫生—儿科]