儿童后尿道瓣膜症瓣膜切开手术对膀胱功能的影响  

Relationship between valve ablation and bladder function in children with posterior urethral valves disorder

作　　者：莫志强 李明磊[2] 谢向辉 张潍平[2] 孙宁[2] 田军[2] 宋宏程[2] 李丹 Mo Zhiqiang;Li Minglei;Xie Xianghui;Zhang Weiping;Sun Ning;Tian Jun;Song Hongcheng;Li Dan(Department of Urology,Shunyi Maternal and Children′s Hospital of Beijing Children′s Hospital,Beijing 101321,China;Department of Urology,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,Beihang University&Capital Medical University,Beijing 100083,China)

机构地区：[1]北京市顺义区妇幼保健院北京儿童医院顺义妇儿医院泌尿外科,北京101321 [2]国家儿童医学中心首都医科大学附属北京儿童医院泌尿外科,北京100045 [3]北京航空航天大学&首都医科大学北京大数据精准医疗高精尖创新中心,北京100083

出　　处：《中华医学杂志》2022年第38期3037-3041,共5页National Medical Journal of China

基　　金：北航-首医大数据精准医疗高精尖创新中心计划(BHME-201913);北京市属医院科研培育计划(PX2017059)。

摘　　要：本研究回顾性分析20例接受后尿道瓣膜症瓣膜切开手术患儿的临床资料,分析其膀胱功能变化。结果显示,手术前、后膀胱顺应性改善,排尿期膀胱最大逼尿肌压力下降,上尿路积水明显改善组残余尿量显著少于未改善组,膀胱顺应性显著高于未改善组,最大尿流率显著高于未改善组(均P<0.05)。结果表明,后尿道瓣膜症瓣膜切开能改善术后膀胱顺应性、最大逼尿肌压力。手术后上尿路积水是否改善与膀胱残余尿量、顺应性、最大尿流率是否改善有关。This study is to investigate the effect of valve ablation on bladder function in patients with posterior urethral valves.The clinical data of patients with posterior urethral valves who received urodynamic examination before and after valve ablation were retrospectively analyzed.The bladder compliance improved during urine storage after operation,and the maximum detrusor pressure decreased during micturition.The postoperative urinary system ultrasound showed that the residual urine volume of the group with significantly improved upper urinary tract hydrocephalus was significantly less than that of the group with no improvement.The bladder compliance was significantly higher than that of the group with no improvement,and the maximum urine flow rate was significantly higher than that of the group with no improvement(all P<0.05).Valve ablation has limited effect on improving bladder function in patients with PUV.Valve incision can help improve the maximum bladder volume,residual urine volume and maximum urinary flow rate.It has a certain effect on bladder compliance and maximum detrusor pressure.

关 键 词：儿童 后尿道瓣膜症 瓣膜切开术 尿流动力学 膀胱功能 

分 类 号：R726.9[医药卫生—儿科]