心律失常患者睡眠状况调查及相关因素分析  

Investigation of sleep status in patients with arrhythmia and analysis of related factors

作　　者：胡立星 刘小宁[1] 任晓庆[1] 贾玉和[1] 楚建民[1] 侯翠红[1] 王靖[1] 牛红霞[1] 张竞涛[1] 赵青[1] 孙旭 叶蕴青[1] 唐闽 华伟[1] Hu Lixing;Liu Xiaoning;Ren Xiaoqing;Jia Yuhe;Chu Jianmin;Hou Cuihong;Wang Jing;Niu Hongxia;Zhang Jingtao;Zhao Qing;Sun Xu;Ye Yunqing;Tang Min;Hua Wei(Center of Arrhythmia,Fuwai Hospital,State Key Laboratory of Cardiovascular Disease,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100037,China)

机构地区：[1]中国医学科学院,北京协和医学院,国家心血管病中心,心血管疾病国家重点实验室,阜外医院心律失常中心,100037

出　　处：《中华心律失常学杂志》2022年第5期433-437,共5页Chinese Journal of Cardiac Arrhythmias

基　　金：国家自然科学基金(U1913210)。

摘　　要：目的了解心律失常患者睡眠质量并探讨其影响因素。方法选取2019年10月至12月在中国医学科学院阜外医院心律失常中心住院的心律失常患者,采用匹兹堡睡眠质量指数(PSQI)测评睡眠质量,以PSQI>7分定义为睡眠障碍,采用多因素Logistic回归分析患者睡眠质量的影响因素。结果入选492例心律失常患者,其中男278例(278/492,56.5%),年龄(55.49±14.93)岁。PSQI为(6.58±4.14)分,睡眠障碍发生率为34.1%(168/492)。多因素Logistic回归分析显示性别(OR=1.76,95%CI 1.17~2.66,P=0.007)、年龄(OR=1.75,95%CI 1.01~2.77,P=0.018)、焦虑(OR=3.72,95%CI 2.24~6.19,P<0.001)、抑郁(OR=1.82,95%CI 1.15~2.88,P=0.010)对心律失常患者睡眠质量有显著影响。女患者睡眠障碍比例显著高于男患者[41.6%(89/214)对28.4%(79/278),χ^(2)=9.33,P=0.002]。≤65岁患者睡眠障碍比例显著低于>65岁患者[31.3%(112/358)对41.8%(56/134),χ^(2)=4.79,P=0.029]。焦虑自评量表评分评估有焦虑情绪患者睡眠障碍比例显著高于无焦虑情绪患者[61.7%(71/115)对25.7%(97/377),χ^(2)=50.82,P<0.001],抑郁自评量表评分评估有抑郁情绪患者睡眠障碍比例显著高于无抑郁情绪患者[50.0%(86/172)对25.6%(82/320),χ^(2)=29.56,P<0.001]。结论心律失常患者睡眠障碍发生率较一般人群高,与年龄、性别、焦虑、抑郁等密切相关。Objective To investigate the sleep quality and related factors among arrhythmia inpatients.Methods Patients with arrhythmia who were hospitalized in Center of Arrhythmia in Fuwai Hospital,from October to December 2019 were selected.The sleep quality was assessed using the Pittsburgh sleep quality index(PSQI),and the total score of PSQI>7 was defined as sleep disorder.Multivariate Logistic regression was used to identify potential influencing factors of sleep quality,and differences were considered statistically significant at the 5%level(P<0.05).Results Four hundred and ninety-two inpatients with arrhythmia were enrolled,including 278 males(278/492,56.5%)with an average age of(55.49±14.93)years.The mean score of PSQI was 6.58±4.14,and 34.1%(168/492)had sleep disorders.Multivariable Logistic regression analysis showed that sleep quality was statistically significantly associated with gender(OR=1.76,95%CI 1.17-2.66,P=0.007),age(OR=1.75,95%CI 1.01-2.77,P=0.018),anxiety(OR=3.72,95%CI 2.24-6.19,P<0.001),and depression(OR=1.82,95%CI 1.15-2.88,P=0.010).The proportions of female patients with sleep disorders was significantly higher than that in male patients[41.6%(89/214)vs.28.4%(79/278),χ^(2)=9.33,P=0.002].The proportion of sleep disorders in patients younger than 65 years old was much lower than those older than 65 years old[31.3%(112/358)vs.41.8%(56/134),χ^(2)=4.79,P=0.029].The proportion of sleep disorders in patients with anxiety was much higher than those without anxiety[61.7%(71/115)vs.25.7%(97/377),χ^(2)=50.82,P<0.001].The proportion of sleep disorders in patients with depression was much higher than those without depression[50.0%(86/172)vs.25.6%(82/320),χ^(2)=29.56,P<0.001].Conclusion The prevalence of sleep disorders in arrhythmia inpatients was higher than that in the general population,and was closely related to gender,age,anxiety,and depression.

关 键 词：心律失常 心性 睡眠障碍 焦虑 抑郁 

分 类 号：R541.7[医药卫生—心血管疾病]