累及双侧泪腺的儿童木村病诊疗体会及临床分析  

Experience and clinical analysis of Kimura disease in children with bilateral lacrimal glands

作　　者：王欣悦 彭粤 高阳[1] 程超 卢蓉[1] WANG Xinyue;PENG Yue;GAO Yang;CHENG Chao;LU Rong(State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,China)

机构地区：[1]中山大学中山眼科中心,眼科学国家重点实验室,广东省眼科视觉科学重点实验室,广东省眼部疾病临床医学研究中心,广州510060

出　　处：《眼科学报》2022年第11期897-901,共5页Eye Science

基　　金：广东省基础与应用基础研究基金自然科学基金(2019A1515010361)。

摘　　要：木村病(Kimura disease,KD)是一种罕见的、病因不明的、可能由免疫介导的慢性进行性炎症性疾病。本文分析1例8岁的男性患者,因左眼无痛性上睑下垂、影像学提示双眼泪腺占位、血象提示嗜酸性粒细胞及免疫球蛋白E(immunoglobulin E,IgE)水平升高、病理提示大量嗜酸性粒细胞浸润,被最终诊断为累及双侧泪腺的KD。行左眼眶肿物切除术后,对患者随访6个月期间未见复发。Kimura disease(KD)is a rare chronic progressive inflammatory disease of unknown etiology that may be immunemediated.Herein,we analyze an 8-year-old male patient who was diagnosed with painless ptosis in the left eye,double tear glands on imaging,elevated levels of eosinophils and immunoglobulin E(IgE)on blood,and massive eosinophil infiltration on pathology.The final diagnosis was Kimura disease involving bilateral lacrimal glands.After resection of the left orbital tumor,no recurrence was observed in the six months postoperation follow-up.

关 键 词：木村病 眼眶肿物 上睑下垂 自身免疫性眼眶疾病 嗜酸性粒细胞增多症 

分 类 号：R725.9[医药卫生—儿科] R777.21[医药卫生—临床医学]