基础免疫是根本, 加强免疫是保障:论疫苗加强免疫及其公共卫生价值  

Basic immunization of vaccines is fundamental, and booster immunization is the guarantee: Booster immunization and its public health value

作　　者：陶泽新 李仁鹏[2] 宋艳艳 徐爱强 Zexin Tao;Renpeng Li;Yanyan Song;Aiqiang Xu(Academy of Preventive Medicine,Shandong University/Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention,Jinan 250014,China;Shandong Center for Disease Control and Prevention,Jinan 250014,China;School of Public Health,Cheeloo College of Medicine,Shandong University,Jinan 250012,China)

机构地区：[1]山东大学预防医学研究院山东省传染病预防控制重点实验室,济南250014 [2]山东省疾病预防控制中心,济南250014 [3]山东大学齐鲁医学院公共卫生学院,济南250012

出　　处：《中华预防医学杂志》2022年第10期1401-1410,共10页Chinese Journal of Preventive Medicine

基　　金：泰山学者工程专项(ts.201511105);泰山学者青年专家计划项目(tsqn.202103187)。

摘　　要：加强免疫是某些疫苗完成基础免疫一段时间后, 为持续保持对某种病原体的免疫力而再次进行的接种。本文对疫苗加强免疫的一些基础理论和常见疫苗加强免疫的作用与效果进行阐述, 探究了在加强免疫方面普遍关注的3个热点问题, 重点强调了"做好疫苗基础免疫是根本, 加强免疫是保障"的公共卫生观点, 以期为提高对加强免疫重要性和必要性的认识、科学指导疫苗免疫工作实践提供科学参考。Booster immunization is the following vaccination after a period of vaccine primary immunization schedule in order to maintain immunity against a certain pathogen.In this article,the immunological mechanism of booster immunization is elaborated,and the effectiveness and public health value of booster immunization for common vaccines is discussed.Subsequently,three hot issues of general concern in booster immunization are addressed,and the public health viewpoint that"Primary immunization of vaccines is fundamental,and booster immunization is the guarantee"is emphasized,so as to raise awareness of the importance and necessity of booster immunization as well as to provide scientific evidences for vaccine immunization practice.

关 键 词：疫苗 公共卫生 加强免疫 价值 

分 类 号：R186[医药卫生—流行病学]