不同压缩感知加速因子对头部3D-T1WI成像质量及基于体素的形态测量定量参数的影响  

Impacts of compressed sensing acceleration factors on imaging quality of head 3D-T1WI and voxel-based morphometry quantitative parameters

作　　者：李贝贝 张浩南 方鑫[1] 胡帅[1] 苗延巍[1] 宋清伟[1] 浦仁旺[1] 刘义军[1] LI Beibei;ZHANG Haonan;FANG Xin;HU Shuai;MIAO Yanwei;SONG Qingwei;PU Renwang;LIU Yijun(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)

机构地区：[1]大连医科大学附属第一医院放射科,辽宁大连116011

出　　处：《中国医学影像技术》2022年第11期1730-1734,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的 观察不同压缩感知(CS)加速因子对头部3D-T1WI及基于体素的形态测量(VBM)定量参数的影响,筛选CS最佳加速因子。方法 对25名成人健康志愿者分别以敏感性编码(SENSE)技术(相位加速因子为3)和不同加速因子(4、6、8、10)CS技术采集头部3D-T1WI,测量3D-T1WI_(SENSE3)、3D-T1WI_(CS4)、3D-T1WI_(CS6)、3D-T1WI_(CS8)及3D-T1WI_(CS10)中的双侧尾状核灰质及胼胝体膝、压部和颅脑顶部白质信号强度(SI)及标准差(SD),计算图像信噪比(SNR)和对比噪声比(CNR),对图像质量进行主观评分;并行VBM,获得全脑体积(TIV)、灰质体积(GMV)、白质体积(WMV)及脑脊液体积(CSFV),比较各3D-T1WI的SNR、CNR、主观评分及VBM定量参数的差异。结果 不同3D-T1WI的SNR、CNR及主观评分差异均有统计学意义(P均<0.05);两两比较,3D-T1WI_(CS6)与3D-T1WI_(SENSE3)的SNR、CNR,3D-T1WI_(CS4)及3D-T1WI_(CS6)与3D-T1WI_(SENSE3)主观评分差异均无统计学意义(P均>0.05),其余图像的SNR、CNR及主观评分差异均有统计学意义(P均<0.05)。基于各3D-T1WI的VBM定量参数TIV、GMV、WMV及CSFV差异均无统计学意义(P均>0.05)。结论 以CS技术采集头部3D-T1WI可在保证成像质量且不影响VBM结果的前提下缩短扫描时间;CS6为最佳加速因子。Objective To observe the impacts of different compressed sensing(CS)acceleration factors on imaging quality of head 3D-T1WI and quantitative parameters of voxel-based morphometry(VBM),and to screen the optimal CS acceleration factor.Methods Head 3D-T1WI of 25 healthy volunteers were collected with sensitivity encoding(SENSE)technology using 3 as phase acceleration factor and 4,6,8,and 10 of CS technology with different acceleration factors,including 3D-T1WI_(SENSE3),3D-T1WI_(CS4),3D-T1WI_(CS6),3D-T1WI_(CS8)及3D-T1WI_(CS10).The signal intensity(SI)and standard deviation(SD)of bilateral caudate nucleus gray matter and white matter of genu,splenium corpus callosum and parietal lobe were measured,then SNR and CNR of images were calculated,and subjective image score was evaluated.The total intracranial volume(TIV),gray matter volume(GMV),white matter volume(WMV)and cerebrospinal fluid volume(CSFV)were obtained with VBM based on 3D-T1WI,and the image signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),subjective score and VBM quantitative parameters were compared.Results There were statistical differences of SNR,CNR and subjective scores among 3D-T1WI(all P<0.05).Paired comparison showed that there was no significant difference of image SNR and CNR of 3D-T1WI_(CS6) and 3D-T1WI_(SENSE3)(all P>0.05),nor of subjective scores of 3D-T1WI_(CS4),3D-T1WI_(CS6) and 3D-T1WI_(SENSE3)(all P>0.05),while significant differences of image SNR,CNR and subjective scores were found among the rest 3D-T1WIs(all P<0.05).There was no significant difference of TIV,GMV,WMV nor CSFV values of VBM quantitative parameters based on 3D-T1WI(all P>0.05).Conclusion Acquisition of head 3D-T1WI with CS could shorten scanning time without affecting VBM results and imaging quality,and CS6 was the optimal acceleration factor.

关 键 词：脑 磁共振成像 压缩感知 基于体素的形态测量 

分 类 号：R322.81[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]