893例食管鳞癌切除标本临床分析  

Clinical analysis of 893 resected specimens of esophageal squamous cell carcinoma

作　　者：黄丛改 刘清 郑树涛 刘涛 谭依依 杨志惠 黄冉 卢晓梅 Huang Conggai;Liu Qing;Zheng Shutao;Liu Tao;Tan Yiyi;Yang Zhihui;Huang Ran;Lu Xiaomei(Clinical Medical Research Institute,the First Affiliated Hospital of Xinjiang Medical University,Xinjiang Urumqi 830054,China;Department of Pathology,the Affiliated Hospital of Southwest Medical University,Sichuan Luzhou 646000,China)

机构地区：[1]新疆医科大学第一附属医院临床医学研究院,新疆乌鲁木齐830054 [2]西南医科大学附属医院病理科,四川泸州646000

出　　处：《中国医刊》2022年第12期1318-1320,共3页Chinese Journal of Medicine

基　　金：新疆维吾尔自治区重点研发专项(2020B03003-1)。

摘　　要：目的分析食管鳞癌的人群分布及临床病理特点。方法选取2014年1月至2021年12月在西南医科大学附属医院接受食管鳞癌手术治疗的患者893例,回顾性分析其临床病理特点。结果893例食管鳞癌患者中61~70岁人群的构成比最高(46.4%,414/893)。临床病理因素分析显示,在食管鳞癌患者中,男性所占比例明显大于女性,肿瘤浸润深度明显高于女性,神经侵犯和淋巴结转移明显多于女性,差异有显著性(P<0.05);此外,分化程度越低的食管鳞癌越易发生脉管侵犯和淋巴结转移,且缩窄型食管鳞癌的浸润深度最高,差异均有显著性(P<0.05)。结论男性食管鳞癌发病率显著高于女性,且更易发生局部浸润和远处淋巴结转移。Objective To analyze the population distribution and clinicopathological features of 893 cases of esophageal squamous cell carcinoma(ESCC).Method A total of 893 cases of large specimens of ESCC surgically resectable from the Affiliated Hospital of Southwest Medical University from January 2014 to December 2021 were retrospectively analyzed.Result Among 893 cases of ESCC,the highest constituent ratio was 46.4%(414/893)in 61-70 years old.The incidence of ESCC in male was significantly higher than that in female(P<0.05).The clinicopathological analysis of the depth of ESCC invasion showed that the depth of tumor invasion was significantly higher in male than female(P<0.05).The clinicopathological analysis of lymph node metastasis of ESCC suggested that male patients were more likely to have lymph node metastasis than female patients(P<0.05).The infiltration depth of constrictive type of ESCC was significantly highest(P<0.05).The lower the differentiation degree of ESCC,the more likely it was to have vascular invasion and lymph node metastasis(P<0.05).Conclusion The incidence of ESCC in males was significantly higher than that in females and local infiltration and distant lymph node metastasis were more likely.

关 键 词：食管鳞癌 临床特点 病理分析 淋巴结转移 

分 类 号：R602[医药卫生—外科学]