基于唾液检测的健康管理研究新进展  

Latest Research Findings on Health Management Based on Saliva Testing

作　　者：梁潇月 杜信眉 周学东[1] LIANG Xiao-yue;DU Xin-mei;ZHOU Xue-dong(State Key Laboratory of Oral Diseases,National Clinical Research Center for Oral Diseases,Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院牙体牙髓病科,成都610041

出　　处：《四川大学学报（医学版）》2022年第6期1110-1117,共8页Journal of Sichuan University(Medical Sciences)

基　　金：国家自然科学基金项目(No.81870754);口腔疾病研究国家重点实验室交叉研究项目(No.2022KXK0402)资助助。

摘　　要：唾液是人体重要的外分泌液之一,能反映机体的健康状态。唾液采集凭借其简单、无痛、快速、安全,且一天内可多次提取等优点,逐步被用于探索检测疾病的生物标志物,同时为病程监控、药物监测、疗效评价等提供依据。基于唾液检测的健康管理,对健康、患病个体收集医疗数据并进行全生命健康周期监测,开展临床队列研究,将信息汇集到健康医疗大数据平台,可管理、指导人群身体状况,定位疾病发生的高危因素,有效干预、预警和评估个体的生命体征,从而加强全生命周期健康管理,全面维护人民健康。同时带动健康产业进步,对国家经济促进具有战略意义,正成为当前最具潜力和应用前景的研究热点,本文就唾液临床检测新技术和基于唾液检测的健康管理作一综述。Being one of the most important exocrine fluids of the human body,saliva can reflect the health status of the body.Soliva collection has various advantages--it is simple,painless,fast,and safe,and soliva can be collected multiple times a day.Therefore,it has been gradually applied in the exploration for biomarkers for disease detection,providing a basis for the monitoring of the course of diseases,medication monitoring,and efficacy evaluation.We should implement health management based on saliva testing,collect the medical data of the healthy and diseased individuals and monitor their whole life cycle health,perform clinical cohort study,aggregate the data on platforms for big data on health and medicine,manage and provide guidance for the health status of populations,pinpoint the high-risk factors for pathogenesis,and provide effective intervention,early warning,and assessment of the vital signs of individuals,thereby reinforcing health management of the whole life cycle and safeguarding people's health in an all-round way.In addition,it drives the development of the health industry and bears strategic significance for the promotion of national economic development.It is becoming a hot research topic promising great potential and impressive applicational prospects.Herein,we reviewed new techniques for clinical saliva testing and health management based on saliva testing.

关 键 词：唾液检测 生物标志物 全生命健康周期 队列研究 健康管理 

分 类 号：R446.19[医药卫生—诊断学]