171例药品不良反应报告回顾性分析及护理应对措施  

Retrospective Analysis of 171 Adverse Drug Reaction Reports and Nursing Countermeasures

作　　者：蔡林雪 江惠玲 CAI Lin-xue;JIANG Hui-ling(The 900th Hospital of the Joint Logistics Team Cang Shan Branch,Fuzhou 350002,China)

机构地区：[1]联勤保障部队第九○○医院仓山院区,福建福州350002

出　　处：《海峡药学》2022年第10期118-120,共3页Strait Pharmaceutical Journal

摘　　要：目的 调查分析医院的药物不良反应发生情况,为改善临床合理用药提供参考。方法 收集某院在2016年9月~2017年8月上报军队药品不良反应监测管理系统的171例药物不良反应报告进行细分汇总。结果 171例ADR报告中,51~60岁年龄段ADR构成比最高;原患疾病最多的为肿瘤;主要涉及抗菌药物、中成药、抗肿瘤及肿瘤辅助用药;静脉途径给药引起的ADR最多;超过四分之三的不良反应发生在给药后1 h内;发生的ADR最常损害皮肤。结论 抗感染类药物发生不良反应的概率最高,皮肤损害是最常见的症状。老年癌症患者在制定药物治疗方案前应详细询问用药史,以减少潜在的相互作用。医药护人员应密切观察用药反应、掌握ADR监测、处理及上报流程,以确保患者用药安全。OBJECTIVE To investigate and analyze the adverse drug reactions in the hospital,and to provide evidence for improving clinical rational drug use.METHODS A subdivision summary of 171 adverse drug reaction reports submitted by a hospital to the military adverse drug reaction monitoring and management system from September 2016 to August 2017 was collected.RESULTS Among the 171 ADR reports,the age group of 51 to 60 years old had the highest ADR proportion;the primary disease was tumor;it mainly involved antibacterial drugs,Chinese patent medicine,anti-tumor,and tumor adjuvant drugs;intravenous administration caused the most ADR;more than three-quarters of adverse reactions occurred within 1 hour of taking;ADRs that occurred most frequently damaged the skin.CONCLUSION Anti-infective drugs have the highest probability of adverse reactions,and skin damage is the most common symptom.Elderly cancer patients should ask for a detailed medication history to reduce potential interactions before making a medication regimen.Medical and nursing staff should closely observe the drug reaction and master the ADR monitoring,processing,and reporting process to ensure the safety of patients’ medication.

关 键 词：药品不良反应 回顾性分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]