探讨某地区献血者ABO正反定型不符的原因及对策  

To expore the cause and countermeasures of ABO positive and negative typing of blood donors in a area

作　　者：张敏 李鹏 曾怡 杨正 ZHANG Min;LI Peng;ZENG Yi;YANG Zheng(The Yichang Blood Center,Yichang,Hubei 443005,China)

机构地区：[1]宜昌市红十字中心血站,湖北宜昌443005

出　　处：《检验医学与临床》2022年第S02期68-70,共3页Laboratory Medicine and Clinic

摘　　要：目的分析献血者ABO正反定型结果不符的试验特点及影响因素,保证临床用血安全。方法回顾性分析宜昌地区2019年1月至2021年12月88例献血者ABO正反定型不符标本。结果收集的88例献血者ABO正反定型不符的主要原因依次为:血清中不规则抗体37.5%(33/88)、ABO亚型18.2%(16/88)、补体因素所致的溶血18.2%(16/88)、反定型试剂15.9%(14/88)、冷凝集素增高5.7%(5/88)、抗体减弱3.4%(3/88)、抗原减弱等1.1%(1/88)。结论对于ABO正反定型不符应认真的分析其原因,鉴定出正确的血型,同时对相应的血液成分是否能应用于临床做出正确的判断,才能保证临床输血的安全性和有效性。Objective To ensure blood transfusion safety,the test characteristics and influencing factors of ABO discrepancy of blood donors were analyzed.Methods Retrospectively analyze 88 cases of blood donors ABO discrepancy from January 2019 to December 2021 in Yichang region.Results The main causes of blood donors ABO discrepancy in our region from high to low is:irregular antibody 37.5%(33/88),ABO subtype 18.2%(16/88),complement cause hemolysis 18.2%(16/88),reagent reason 15.9%(14/88),cold agglutinin 5.7%(5/88),antibody reduce 3.4%(3/88),antigen reduce 1.1%(1/88).Conclusion The causes of ABO discrepancy should be analyze and identify the correct blood type to make a correct judgment on whether the corresponding blood components can be applied to clinical,in order to ensure the safety and effectiveness of blood transfusion.

关 键 词：献血者 血型鉴定 ABO正反不符 输血安全 

分 类 号：R446.6[医药卫生—诊断学]