酒店式方舱医院奥密克戎变异株感染患者出院后病房环境病毒监测  

Surveillance of virus in ward environment of patients with SARS-CoV-2 omicron infection in hotel-style Fangcang shelter hospital after discharge

作　　者：徐琳智 张勤[1] 钱国清[2] 叶智学[3] 孙维杰 蔡海娜[5] XU Lin-zhi;ZHANG Qin;QIAN Guo-qing;YE Zhi-xue;SUN Wei-jie;CAI Hai-na(Ningbo First Hospital,Ningbo,Zhejiang 315010,China)

机构地区：[1]宁波市第一医院院感科,浙江宁波315010 [2]宁波市第一医院感染科,浙江宁波315010 [3]宁波市第一医院注射室,浙江宁波315010 [4]宁波市第一医院检验科,浙江宁波315010 [5]宁波市第一医院护理部,浙江宁波315010

出　　处：《中华医院感染学杂志》2022年第20期3197-3200,共4页Chinese Journal of Nosocomiology

基　　金：浙江省医药卫生科技计划基金资助项目(2022KY1116)。

摘　　要：目的对酒店改造式方舱医院新型冠状病毒奥密克戎BA.2变异株(Omicron BA.2)感染患者出院后病房环境病毒残留监测,指导临床防控与消杀工作。方法以2022年4月5-27日宁波市慈溪达蓬山方舱医院收治的30例Omicron感染的患者为研究对象,收集患者入院时的一般情况,对出院后病房内环境(门把手、床头柜、枕头、木地板、座便器、墙面和电源开关)等物体表面开展样本采集,进行核酸检测分析。结果30例Omicron感染者的中位数年龄为36.00岁,发热40.00%(12/30),平均住院时间为(13.33±2.10)天,新型冠状病毒疫苗接种率为93.33%(28/30);入院时核酸检测的N基因Ct平均值为23.71,ORF1ab基因Ct平均值为24.82;患者出院前1 d到出院后6 d,病房内床头柜的核酸阳性检测率分别为80.00%~21.44%,木地板的核酸阳性检测率分别为83.33%~42.86%,门把手的核酸阳性检测率为15.03%~12.50%,枕头的核酸阳性检测率为46.70%~14.33%,座便器的核酸阳性检测率为26.76%~14.33%,电源开关的核酸阳性检测率为27.56%~14.33%,而墙面的核酸阳性检测率为0。结论病房内病毒检出阳性率以木地板和床头柜最高,依次是枕头、电源开关、座便器、门把手和墙面,对酒店改造式方舱医院的院感防控和环境消杀工作具有较高的应用价值和借鉴意义。OBJECTIVE To monitor the virus residues in the ward environment of the patients infected with the new coronavirus Omicron BA.2 after discharge from the hotel-renovated Fangcang shelter hospital,and to provide basis and guidance for the clinical prevention and control and disinfection work.METHODS Thirty Omicron BA.2-infected patients admitted to the Dapengshan hotel Fangcang shelter hospital in Cixi city of Ningbo from Apr.5 to 27,2022 were selected as the research subjects.The general features of 30 patients with Omicron variant infection on admission were collected,and the samples of the ward environment such as door handle,bedside table,pillow,wooden floor,toilet,wall,and power switch were taken after discharge,and nucleic acid detection and analysis were conducted.RESULTS The median age of the 30 Omicron BA.2-infected patients was 36.00 years,there were 40%(12/30)cases having fever,the average hospitalization time was(13.33±2.10)days,and there were 93.33%(28/30)cases receiving two and three doses of vaccination.The mean value of the cycle threshold of nucleic acid detection of the N gene was 23.71,and the average Ct of ORF1 ab gene was 24.82.From 1 d before discharge to 6 d after discharge,the nucleic acid positive detection rate of the bedside table in the ward was 80.00%-21.44%,and the positive detected rate of the wooden floor was 83.33%-42.86%,and the positive detection rate of the door handle was 15.03%-12.50%,and the positive detection rate of the pillow was 46.70%-14.33%.and the positive detection rate of the toilet is 26.76%-14.33%,and the positive detection rate of the power switch is 27.56%-14.33%,whereas the positive detection rate of the wall is 0.CONCLUSION The positive detection rate of Omicron BA.2 in the hotel Fangcang hospital ward was the highest with wooden floor and bedside table,followed by pillow,power switch,toilet,door handle and wall,which had high application value and reference significance for the prevention and control of nosocomial infection and environmental disinfection in the

关 键 词：酒店式方舱医院 新型冠状病毒 奥密克戎变异株 环境监测 

分 类 号：R183[医药卫生—流行病学]