中药调节肠道微生态治疗慢传输型便秘的研究进展  

Research Progress on Traditional Chinese Medicine Treatment of Regulating Gut Microbiota in Slow Transit Constipation

作　　者：丁一宁 于飞[1] DING Yining;YU Fei(Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning,China)

机构地区：[1]中国医科大学附属盛京医院,辽宁沈阳110004

出　　处：《中华中医药学刊》2022年第10期206-209,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：辽宁省科学技术计划项目(2012225021);辽宁省中医药临床学(专)科能力建设项目(LNZYXZK201905)。

摘　　要：慢传输型便秘(STC)是临床最常见的慢性功能性便秘的一种,除了具有粪质干硬、排便困难、排便次数少等慢性功能性便秘具有的特点之外,其特有的诊断特征为结肠传输能力减弱、传输速度减缓。STC的病因繁杂,发病机制目前尚不明确,可能与Cajal细胞、胃肠神经递质、激素、肠道菌群及心理因素异常等有关。近来的研究证实肠道菌群是STC发病的因素之一,临床上中医药对STC有很好的疗效,将视角放在菌群失调导致STC发病这一侧重点上,对近年来中医药调节肠道菌群治疗STC的研究进行综述,以期为STC的临床治疗与研究提供参考。In addition to the characteristics of chronic functional constipation, such as dry stool, difficult defecation and less frequency of defecation, slow transit constipation(STC) is characterized by reduced colonic transmission capacity and slow transmission speed. The etiology of STC is complex and may be closely related to abnormalities of Cajal cells, gastrointestinal neurotransmitters, hormones, intestinal flora and psychological factors. Gut microbiota, as one of the factors affecting the incidence of STC,is also regarded as the “second brain” of the human body, and plays an important role in a variety of biological processes of the human body. As a research hotspot in recent years, the imbalance of bacterial community has been proved to lead to the diseases of many human systems. This paper focuses on the side that bacterial imbalance leads to STC,and reviews the research on the regulation of intestinal flora by traditional Chinese medicine in the treatment of STC in recent years, in order to provide reference for the clinical treatment and research of STC.

关 键 词：慢传输型便秘 肠道菌群 中医药 研究进展 

分 类 号：R256.35[医药卫生—中医内科学]