机械支架取栓对急性脑血管闭塞患者血管再通率及神经功能恢复的影响分析  

Effect of Mechanical Stent Thrombectomy on Vascular Recanalization Rate and Neurological Recovery in Patients with Acute Cerebral Vascular Occlusion

作　　者：周寅 ZHOU Yin(Department of Neurology,Zhangjiagang Hospital Affiliated to Soochow University,Zhangjiagang,Jiangsu Province,215600 China)

机构地区：[1]苏州大学附属张家港医院神经内科,江苏张家港215600

出　　处：《世界复合医学》2022年第9期45-49,共5页World Journal of Complex Medicine

摘　　要：目的探讨急性脑血管闭塞应用机械支架取栓对血管再通率与神经功能恢复的影响效果。方法选取2019年1月—2021年12月苏州大学附属张家港医院收治的120例急性脑血管闭塞患者,根据治疗方案不同分为两组,每组60例。对照组采用溶栓治疗,观察组采用机械支架取栓治疗。比较两组治疗效果。结果观察组血管再通率85.00%,高于对照组63.33%,差异有统计学意义(χ^(2)=7.351,P<0.05);观察组术后1、7 d神经功能评分分别为(7.54±2.25)分、(3.03±1.01)分,低于对照组的(10.57±2.88)分、(5.54±1.64)分,差异有统计学意义(t=6.422、10.094,P<0.05);观察组术后3个月、6个月mRS评分分别为(2.60±0.58)分、(0.81±0.35)分,低于对照组的(3.04±0.72)分、(1.45±0.63)分,差异有统计学意义(t=3.686、6.879,P<0.05);观察组术后24 h出血率为8.33%,低于对照组的21.67%,差异有统计学意义(χ^(2)=4.183,P<0.05);此外,观察组术后SF-36各项评分均高于对照组,差异有统计学意义(P<0.05)。结论急性脑血管闭塞应用机械支架取栓治疗,相比溶栓治疗,可提高血管再通率,更好地改善患者的神经功能,促进预后提高,同时明显减少术后出血,改善生活质量。Objective To investigate the effect of mechanical stent thrombectomy on vascular recanalization rate and neurological recovery in acute cerebral vascular occlusion.Methods 120 patients with acute cerebrovascular occlusion admitted to Zhangjiagang Hospital Affiliated to Suzhou University from January 2019 to December 2021 were selected and divided into two groups according to different treatment schemes,with 60 patients in each group.The control group was treated with thrombolytic therapy,and the observation group was treated with mechanical stent thrombectomy.The therapeutic effects of the two groups were compared.Results The vascular recanalization rate in the observation group was 85.00%,which was higher than that in the control group(63.33%),and the difference was statistically significant(χ^(2)=7.351,P<0.05).The neurological function scores of the observation group at 1 d and 7 d after operation were(7.54±2.25)points and(3.03±1.01)points,respectively,which were lower than those of the control group(10.57±2.88)points and(5.54±1.64)points,and the differences were statistically significant(t=6.422,10.094,P<0.05).The mRS scores of the observation group were(2.60±0.58)points and(0.81±0.35)points 3 months and 6 months after operation,respectively,which were lower than those of the control group(3.04±0.72)points and(1.45±0.63)points,and the differences were statistically significant(t=3.686,6.879,P<0.05).The bleeding rate at 24 h after operation in the observation group was8.33%,which was lower than 21.67%in the control group,and the differences were statistically significant(χ^(2)=4.183,P<0.05).In addition,the postoperative SF-36 scores in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with thrombolytic therapy,mechanical stent thrombectomy for acute cerebral vascular occlusion can improve the recanalization rate,better improve the neurological function of patients,and promote the improvement of prognosis.At th

关 键 词：急性脑血管闭塞 机械支架取栓 溶栓术 血管再通率 神经功能 生活质量 

分 类 号：R4[医药卫生—临床医学]