综合监护病房泛耐药鲍曼不动杆菌医院感染危险因素及疾病转归分析  

Analysis of nosocomial infection risk factors and disease outcome of XDRAB in general care unit

作　　者：陈晓君 陈红[1] 张彬[1] 王跃国[1] 徐晓耘[1] 顾李琴[1] CHEN Xiao-jun;CHEN Hong;ZHANG Bin;WANG Yue-guo;XU Xiao-yun;GU Li-qin(Affiliated Hospital of Nantong University,Nantong Jiangsu 226001,China)

机构地区：[1]南通大学附属医院,江苏南通226001

出　　处：《中国消毒学杂志》2022年第10期776-778,782,共4页Chinese Journal of Disinfection

基　　金：南通市科技项目(HS2020001);南通市卫生和计划生育委员会科研项目(QA2020066);南通大学附属医院院级课题(Tfg1904)。

摘　　要：目的 探讨某院综合监护病房泛耐药鲍曼不动杆菌(XDRAB)医院感染的危险因素及疾病转归情况。方法 选取2018—2020年在该院综合监护病房内发生XDRAB感染患者62例为感染组,同期未发生医院感染患者62例为对照组,利用回顾性研究分析2组患者医院感染危险因素及疾病转归情况并进行分析。结果 呼吸系统感染占75.8%,其次为血液系统感染,占11.3%。单因素分析和多因素Logistic回归分析显示,住ICU>7 d、机械通气>4 d和抗菌药物使用>14 d是ICU患者感染XDRAB的独立危险因素(P<0.05)。XDRAB感染组医疗费用比未感染组多158 436.5元(P<0.01)。感染组患者死亡率(17.74%)明显高于未感染组(1.61%)(P<0.01)。结论 ICU XDRAB院内感染以呼吸系统感染为主,住ICU>7 d、机械通气>4 d和抗菌药物使用>14 d是ICU患者发生XDRAB医院感染的独立危险因素。Objective To discuss the risk factors of nosocomial infection and disease outcome of XDRAB in the general care unit of our hospital. Methods This study selected 62 patients with XDRAB infection in general care unit of our hospital from 2018 to 2020 as the infection group, and 62 patients without nosocomial infection during the same period as the control group.Retrospective research was used to analyze the risk factors of nosocomial infection and disease outcome of the two groups of patients and conducted statistical analysis. Results Nosocomial infections of ICU XDRAB in our hospital were mainly respiratory system infections, accounting for 75.8%,followed by blood system infections, accounting for 11.3%.The results of the univariate analysis and multivariate Logistic regression analysis showed that staying in ICU for more than 7 d, mechanical ventilation for more than 4 d, and use of antibacterial drugs for more than 14 d were independent risk factors for XDRAB infection in ICU patients(P<0.05).The medical expenses of the XDRAB infection group were 158 436.5 yuan more than that of the uninfected group(P<0.01).The mortality of patients in the infected group [17.74%(11/62)] was significantly higher than that in the non-infected group [1.61%(1/62)](P<0.01). Conclusions Nosocomial infections of XDRAB in the ICU of our hospital are mainly respiratory infections.Staying in ICU for more than 7 d, mechanical ventilation for more than 4 d, and use of antibacterial drugs for more than 14 d are independent risk factors for XDRAB nosocomial infection in ICU patients.

关 键 词：综合监护病房 泛耐药鲍曼不动杆菌 医院感染 危险因素 疾病转归 

分 类 号：R183[医药卫生—流行病学]