男性人群生活行为及饮食习惯与食管癌发病关系对照研究  

Case Control Study on Relationship Between Life Style,Eating Habits and Incidence of Esophageal Cancer in Male Population

作　　者：郑玉玲[1] 张亚玲[1] 陈玉龙[1] 宋学坤[1] 代民涛 徐学琴[1] 董玉琼[1] 马纯政 解英[3] 舒琦瑾[4] 薛文翰[5] 李平[6] 范焕芳[7] 罗保平[8] 郑智[9] 李晓龙 张洪亮 周超峰 许彦超 李小青 王泽坤 朱然培 张华[1] 周哲旭 张帆[1] 张瑞[1] ZHENG Yuling;ZHANG Yaling;CHEN Yulong;SONG Xuekun;DAI Mintao;XU Xueqin;DONG Yuqiong;MA Chunzheng;XIE Ying;SHU Qijin;XUE Wenhan;LI Ping;FAN Huanfang;LUO Baoping;ZHENG Zhi;LI Xiaolong;ZHANG Hongliang;ZHOU Chaofeng;XU Yanchao;LI Xiaoqing;WANG Zekun;ZHU Ranpei;ZHANG Hua;ZHOU Zhexu;ZHANG Fan;ZHANG Rui(Henan University of Chinese Medicine,Zhengzhou Henan China 450046;Henan Province Hospital of Traditional Chinese Medicine/The Second Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou Henan China 450002;Shanxi Provincial Cancer Hospital,Taiyuan Shanxi China 030013;Zhejiang Provincial Hospital of Chinese Medicine,Hangzhou Zhejiang China 310006;Gansu Provincial Cancer Hospital,Lanzhou Gansu China 730000;The First Affiliated Hospital of Anhui Medical University,Hefei Anhui China 230000;Hebei Province Hospital of Traditional Chinese Medicine,Shijiazhuang Hebei China 050000;Hubei Province Hospital of Traditional Chinese Medicine,Wuhan Hubei China 430061;Jiangxi Cancer Hospital,Nanchang Jiangxi China 330029;Ningxia Chinese Medicine Research Center,Yinchuan Ningxia China 750021;Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region,Wulumuqi Xinjiang China 830000)

机构地区：[1]河南中医药大学,河南郑州450046 [2]河南省中医院/河南中医药大学第二附属医院,河南郑州450002 [3]山西省肿瘤医院,山西太原030013 [4]浙江省中医院,浙江杭州310006 [5]甘肃省肿瘤医院,甘肃兰州730000 [6]安徽医科大学第一附属医院,安徽合肥230000 [7]河北省中医院,河北石家庄050000 [8]湖北省中医院,湖北武汉430061 [9]江西省肿瘤医院,江西南昌330029 [10]宁夏回族自治区中医医院暨中医研究院,宁夏银川750021 [11]新疆维吾尔自治区中医医院,新疆乌鲁木齐830000

出　　处：《中医学报》2022年第12期2582-2586,共5页Acta Chinese Medicine

基　　金：国家中医临床研究基地科研专项项目(2019JDZX001,2019JDZX028);河南省高等学校重点科研项目(20A360005);河南省科技攻关社会发展项目(202102310497);国家中医药百千万人才支持计划项目-岐黄学者{国中医药人教发[2018]284号}。

摘　　要：目的:了解男性人群生活行为及饮食习惯与食管癌发病的关系,为男性人群食管癌的预防控制提供参考依据。方法:采用以医院为基础的病例对照研究方法,2020年6月至2021年3月在全国10个省份,将1552例经病理确诊食管癌的男性作为病例组,将同一地方甚至同一家庭的1095例男性非健康人作为对照组,对两组人员进行电子问卷调查。结果:多因素Logistic回归分析结果显示,饮酒史、食热烫食物、吃硬质食物、暴饮暴食、霉变食物可使男性人群食管癌的发病风险增加,口腔清洁情况≥1次·d^(-1)使男性人群食管癌的发病风险降低。结论:饮酒史、口腔清洁情况及是否食热烫食物、吃硬质食物、暴饮暴食、吃霉变食物等饮食习惯是男性人群食管癌发病的主要影响因素。Objective:To understand the relationship between life behavior and eating habits of the male population and the incidence of esophageal cancer(EC),and to provide reference for the prevention and control of esophageal cancer in the male population.Methods:A hospital-based case-control study was used.From June 2020 to March 2021,1552 males with pathologically diagnosed EC were used as the case group,and 1095 healthy males from the same place or even the same family were used as the control group.Electronic questionnaires were conducted on these two groups.Results:Multivariate logistic regression analysis showed that drinking history,eating hot food,hard food,overeating,and eating moldy food can increase the risk of EC in men.And the risk of EC is reduced in males with oral hygiene≥1 time·day^(-1).Conclusions:The history of drinking,oral hygiene,whether to eat hot food,hard food,overeating,eating moldy food and other dietary habits are the main influencing factors for the incidence of EC in males.

关 键 词：食管癌 生活行为 饮食习惯 病例对照研究 调查问卷 男性 

分 类 号：R273[医药卫生—中西医结合]