浙江省新型冠状病毒肺炎本土感染者流行特征  

Epidemiological characteristics of local COVID-19 cases in Zhejiang Province

作　　者：王臻[1] 刘碧瑶[1] 戚小华[1] 张人杰[1] 边俏 江敏[1] WANG Zhen;LIU Biyao;QI Xiaohua;ZHANG Renjie;BIAN Qiao;JIANG Min(Department of Health Emergency,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)

机构地区：[1]浙江省疾病预防控制中心应急部,浙江杭州310051

出　　处：《预防医学》2022年第12期1240-1244,共5页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：浙江省卫生健康科技计划项目(2022PY048);浙江省公益技术研究计划(GF21H260014)。

摘　　要：目的了解2022年3—5月浙江省新型冠状病毒肺炎(COVID-19)本土感染者的流行特征,为防控COVID-19疫情提供依据。方法通过中国疾病预防控制信息系统收集2022年3—5月浙江省COVID-19本土感染者个案资料和现场流行病学调查信息,采用描述性流行病学方法分析感染时间、地区、人群分布、发现途径等流行特征和疫苗加强接种情况;采用多因素logistic回归模型分析本土感染者临床症状严重程度的影响因素。结果2022年3—5月浙江省共报告289起本土疫情,均由Omicron变异株引起,累计报告感染者1598例,其中确诊病例672例,占42.05%;无症状感染者926例,占57.95%。确诊病例中,轻型614例,占91.37%;普通型58例,占8.63%;无重型、危重型和死亡病例报告。以7起感染者数≥50例疫情计算,感染者社区清零时间为(6.14±1.07)d,疫情持续时间为(13.43±4.39)d,疫情达到高峰时间为(3.00±1.63)d。感染者主要通过集中隔离点检测发现,1105例占69.15%。完成新型冠状病毒(新冠病毒)疫苗加强接种843例,占52.75%。多因素logistic回归分析结果显示,年龄(≥60岁为参照,6~<18岁,OR=0.111,95%CI:0.024~0.508;18~<45岁,OR=0.341,95%CI:0.163~0.713)、新冠病毒疫苗加强接种(OR=0.219,95%CI:0.117~0.410)是感染后发生严重临床症状的保护因素。结论2022年3—5月浙江省COVID-19本土疫情均由Omicron变异株引起,感染者临床症状较轻;学龄前儿童、中老年人群和未完成新冠病毒疫苗加强接种人群感染后临床症状相对较重。Objective To analyze the epidemiological characteristics of coronavirus disease 2019(COVID-19)local infec⁃tions in Zhejiang Province during the period between March and May,2022,so as to provide the evidence for COVID 19 control.Methods The individual investigation data and field epidemiological investigation data of local COVID-19 cases in Zhejiang Province from March to May 2022 were extracted from the National Diseases Prevention and Control Information System of China.The temporal,spatial and population distribution,identification and booster vaccination of local COVID-19 cases were analyzed using a descriptive epidemiological method.Factors affecting the severity of clini⁃cal symptoms were identified among local COVID-19 cases using a multivariable logistic regression model.Results A total of 289 local COVID-19 epidemics occurred in Zhejiang Province from March to May 2022,and all infections were caused by the Omicron variant.A total of 1598 local COVID-19 infections were reported,including 672 con⁃firmed cases(42.05%)and 926 asymptomatic cases(57.95%),and the 672 confirmed case included 614 mild cases(91.37%),58 normal cases(8.63%),while no severe,critically ill or dead cases were reported.The mean duration of COVID-zero community, mean duration of COVID-19 epidemics and mean length to COVID-19 peak calculated accord⁃ ing to 7 epidemics with 50 and more cases were (6.14±1.07), (13.43±4.39), (3.00±1.63) d, respectively. COVID-19 infec⁃ tion was predominantly detected in centralized quarantine sites (1 105 cases, 69.15%), and 843 cases completed booster immunization of COVID-19 vaccines (52.75%). Multivariable logistic regression analysis showed that age (with ages of 60 years and older as the reference, age of 6 to 17 years, OR=0.111, 95%CI: 0.024-0.508;age of 18 to 44 years, OR= 0.341, 95%CI: 0.163-0.713) and booster COVID-19 vaccination (OR=0.219, 95%CI: 0.117-0.410) were protective factors for developing more severe clinical symptoms following COVID-19 infections. Conclusions All local COVID-

关 键 词：新型冠状病毒肺炎 Omicron变异株 本土疫情 加强接种 

分 类 号：R181.3[医药卫生—流行病学]