褪黑素及其受体对哺乳动物卵巢调控作用机制的研究进展  

Research Progress on the Regulatory Mechanisms of Melatonin and Its Receptor on Mammalian Ovary

作　　者：刘子嶷 刘玉芳 储明星[1] LIU Ziyi;LIU Yufang;CHU Mingxing(Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture and Rural Affairs,Institute of Animal Science of Chinese Academy of Agricultural Sciences,Beijing 100193,China)

机构地区：[1]中国农业科学院北京畜牧兽医研究所,农业农村部动物遗传育种与繁殖重点实验室,北京100193

出　　处：《中国草食动物科学》2022年第6期45-49,共5页China Herbivore Science

基　　金：国家自然科学基金项目(32172704);财政部和农业农村部国家现代农业产业技术体系(CARS-38);中国农业科学院科技创新工程(CAAS-ZDRW202106,ASTIP-IAS13)。

摘　　要：褪黑素是一种胺类激素,广泛存在于多种动物体内,具有较强的抗细胞衰老和抗氧化应激的效果,在哺乳动物的器官、组织和细胞中参与重要的生理活动过程,同时也在动物卵巢卵泡的生长、发育、排卵等重要繁殖过程中发挥着不可忽视的调控作用。文章综述了哺乳动物卵泡的生长发育及排卵过程、褪黑素的生物学功能、褪黑素受体信号的转导作用和褪黑素对哺乳动物卵巢的调控作用,以期为研究褪黑素在未来畜牧业生产中的应用提供参考。Melatonin is an amine hormone that plays an important role in regulating mammalian reproduction.Melatonin exists widely in many kinds of animals,has strong anti-cell aging and antioxidant stress effects.It takes involvement in crucial physiological processes in mammalian tissues,cells and organs.At the same time,melatonin also plays an important role in regulating the growth,development and ovulation of animal ovarian follicles.This paper expounded the follicular development and ovulation process,the biological function of melatonin,the signal transduction of melatonin receptor and the regulation of ovary,so as to serve as a guide for future melatonin production techniques and applications in animal husbandry.

关 键 词：褪黑素 卵巢 褪黑素受体 调控机制 

分 类 号：S814.1[农业科学—畜牧学]