妊娠期女性不同孕期血清维生素A、K_(1)水平检测及意义  

Detection and significance of serum vitamin A and K_(1) levels in pregnant women at different stages of pregnancy

作　　者：朱玉兰 Zhu Yulan(Department of Obstetrics and Gynecology,Jinxi People's Hospital of Kunshan,Kunshan,Jiangsu 215300,China)

机构地区：[1]昆山市锦溪人民医院妇产科,江苏昆山215300

出　　处：《实用妇科内分泌电子杂志》2021年第29期7-9,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨妊娠期维生素A预防干预后水平及维生素K_(1)水平现状。方法选取孕妇1083名,采集妊娠中期(24~28周)维生素A血清标本858份,观察组共420例,未额外补充维生素A,仅予以饮食指导;对照组438例,予以每天补充维生素A滴剂(含维生素A 1800单位)妊娠晚期(32~34周)维生素K_(1)血清标本225份。测定并比较不同情况下的血清维生素A、维生素K_(1)的水平。结果观察组维生素A测定偏低率均高于对照组,差异具有统计学意义(P<0.05),两组维生素A测定偏高率、两组妊娠中期维生素A测定偏低率、正常率比较,两组妊娠中期不同年龄段血清维生素A水平比较,差异无统计学意义(P>0.05)。225例妊娠晚期孕妇中血清维生素K_(1)水平正常200例(88.89%),偏高25例(11.11%)。结论妊娠期通过额外补充维生素A可有效改善妊娠期维生素A水平;正常孕妇妊娠期不需要额外常规补充维生素K_(1)。Objective To investigate the serum vitamin A levels in pregnant women after preventive intervention and status quo of vitamin K_(1)levels.Methods A total of 1083 pregnant women were selected,including 858 vitamin A serum samples in the second trimester(24~28 weeks),a total of 420 cases in the observation group were not supplemented with vitamin A and were only given dietary guidance;the control group 438 cases were supplemented with daily vitamin A drops(containing 1800 units of vitamin A),and 225 vitamin K_(1)serum samples in the third trimester(32~34 weeks).The levels of serum vitamin A and vitamin K_(1)under different conditions were detected and compared.Results The low rate of vitamin A determination in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in serum vitamin A levels between the two groups at different ages in the second trimester of pregnancy(P>0.05).Among the 225 pregnant women in the third trimester,serum vitamin K_(1)levels were normal in 200 cases(88.89%)and high in 25 cases(11.11%).Conclusion Additional vitamin A supplementation during pregnancy can effectively improve vitamin A levels during pregnancy;normal pregnant women do not need additional routine vitamin K_(1)supplementation during pregnancy.

关 键 词：维生素A 维生素K1 预防干预 妊娠期 

分 类 号：R714[医药卫生—妇产科学]