海南省三亚地区孕晚期产妇胃肠道和生殖道GBS定植对妊娠结局和新生儿GBS疾病的影响  

Effects of GBS colonization in the gastrointestinal and reproductive tracts of late pregnant women on pregnancy outcomes and neonatal GBS disease in Sanya, Hainan Province

作　　者：麦燕 赵梅 钱沁佳 麦燕婷 Mai Yan;Zhao Mei;Qian Qinjia;Mai Yanting(Department of Obstetrics and Gynecology,Sanya Central Hospital,Sanya,Hainan 572000,China,Sanya Central Hospital,Sanya,Hainan 572000,China;Department of Pharmacy;Department of Hematology,Sanya Central Hospital,Sanya,Hainan 572000,China)

机构地区：[1]三亚中心医院妇产科,海南三亚572000 [2]三亚中心医院药学部,海南三亚572000 [3]三亚中心医院血液科,海南三亚572000

出　　处：《实用妇科内分泌电子杂志》2021年第29期37-39,共3页Electronic Journal of Practical Gynecological Endocrinology

基　　金：海南省卫生计生行业科研项目(编号18A200164)。

摘　　要：目的 探究海南省三亚地区孕晚期产妇胃肠道和生殖道B族链球菌(GBS)定植的影响。方法 选择560例晚期孕产妇,根据GBS检测结果将其分为阳性组(58例)和阴性组(502例)。分析各项观察指标。结果 阳性组中初产妇、有GBS感染史、甲状腺功能异常发生率,胎膜早破,宫内感染发生率以及新生儿的脑膜炎、肺炎及败血症发生率明显高于阴性组,差异具有统计学意义(P<0.05)。结论 海南省三亚地区孕晚期产妇胃肠道和生殖道GBS定植会导致不良妊娠结局,应做好GBS筛查、预防及控制工作,提高母婴健康水平。Objective To investigate the effect of group B Streptococcus(GBS) colonization in the gastrointestinal and reproductive tracts of late pregnant women in Sanya of Hainan. Methods A total of 560 late pregnant women were selected and divided into the positive group(58 cases) and the negative group(502 cases) according to the GBS test results. The indicators of the research object were analyzed. Results In the positive group, the incidences of primipara, GBS infection history, thyroid dysfunction, premature rupture of membranes and intrauterine infection, neonatal meningitis, pneumonia and sepsis were significantly higher than those in the negative group, and the differences were statistically significant(P<0.05). Conclusion GBS colonization in the gastrointestinal and reproductive tracts of late pregnant women in Sanya of Hainan can lead to adverse pregnancy outcomes. GBS screening, prevention and control should be done to improve the health of mothers and babies.

关 键 词：B族链球菌 孕晚期 胃肠道 生殖道 妊娠结局 

分 类 号：R714.2[医药卫生—妇产科学]