慢性气道炎症性疾病对新型冠状病毒肺炎的影响  

Impact of chronic airway inflammatory diseases on COVID‐19

作　　者：索涛[1] 范慧[1] 陈国忠[1] SUO Tao;FAN Hui;CHEN Guozhong(Dept.of Respiratory and Critical Care Medicine,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)

机构地区：[1]武汉大学人民医院呼吸与危重症医学科,湖北武汉430060

出　　处：《武汉大学学报（医学版）》2022年第6期878-884,共7页Medical Journal of Wuhan University

摘　　要：新型冠状病毒肺炎(COVID⁃19)大流行造成了大量患者住院和死亡,产生了重大的社会经济影响。多项研究已证实COVID⁃19的严重程度与多种危险因素有关,如年龄、男性、高血压、糖尿病、肥胖、心血管疾病、肝脏和肾脏疾病、肿瘤及妊娠等。慢性阻塞性肺疾病(COPD)和支气管哮喘作为人群最常见的慢性气道炎症性疾病,其与新型冠状病毒感染的确切联系目前尚不明确。本文将对COVID⁃19患者COPD及哮喘的共病率以及它们对COVID⁃19的影响及可能机制等作一综述,以期为临床实践提供科学资料。The COVID⁃19 pandemic causes an overwhelming number of hospitalization and deaths with a significant socioeconomic impact.Several studies have linked the severity of COVID⁃19 to risk factors such as age,male,hypertension,diabetes,obesity,cardiovascular disease,liver and kidney disease,cancer,and pregnancy.The association between chronic obstructive pulmonary disease(COPD)and asthma,the most common chronic airway inflammatory diseases in the population,and SARS⁃CoV⁃2 infection is not yet clear.This article will review the comorbidity rates of COPD and asthma in COVID⁃19 patients,their effects on COVID⁃19,and the possible mechanisms,in order to provide scientific data for clinical practice.

关 键 词：慢性阻塞性肺疾病 哮喘 新型冠状病毒肺炎 SARS⁃CoV⁃2 

分 类 号：R563.1[医药卫生—呼吸系统]