颈动脉支架成形术对颈内动脉重度狭窄患者认知功能的影响  

Effects of CAS on Cognition in Patients with Severe Internal Artery Stenosis

作　　者：党利 王长爽 DANG Li;WANG Chang-shuang(Nanyang Central Hospital,Henan Nanyang 473009)

机构地区：[1]南阳市中心医院,河南南阳473009

出　　处：《深圳中西医结合杂志》2022年第17期17-20,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:分析颈动脉支架成形术(CAS)对颈内动脉重度狭窄患者认知功能的影响。方法:选取南阳市中心医院2020年8月至2021年8月期间收治的78例颈内动脉重度狭窄患者,随机数字表法分为观察组与对照组,各39例。对照组患者行颈动脉内膜切除术(CEA),观察组患者行CAS手术;术后随访6个月,比较两组患者手术效果及认知功能改善情况。结果:术前两组患者的蒙特利尔认知评估量表(MoCA)、简易智力状态检查量表(MMSE)、尿语言流畅性测验(VFT)、本顿视觉保持测验(BVRT)、日常生活活动(ADL)评分比较,差异无统计学意义(P>0.05);术后6个月观察组患者的MoCA、MMSE、VFT、BVRT、ADL评分均高于对照组,差异具有统计学意义(P<0.05)。观察组患者的并发症发生率(2.56 %)低于对照组(15.38 %),差异具有统计学意义(P<0.05)。结论:CAS手术耗时短、创伤性小,可迅速疏通颈动脉,增加脑部血氧量,改善颈内动脉重度狭窄患者的认知功能,且并发症少。Objective To analyze the effect of carotid artery stenting (CAS) on cognitive function in patients with severe internal artery stenosis.Methods A total of 78 patients with severe internal carotid artery stenosis admitted to Nanyang Central Hospital from August 2020 to August 2021 were selected and randomly divided into an observation group and a control group with the random number table method,39 cases in each group.The control group received carotid endarterectomy (CEA),and the observation group received CAS.The postoperative follow-up was 6 months,and the operation effect and cognitive function improvement were compared between the two groups.Results There was no significant difference in the scores of Montreal cognitive assessment (MoCA),mini-mental state examination (MMSE),verbal fluency test (VFT),Benton visual retention test (BVRT) and activities of daily living (ADL) between the two groups before operation (P > 0.05).6 months after operation,the scores of MoCA,MMSE,VFT,BVRT and ADL in the observation group were higher than those in the control group,and the differences were statistically significant (P < 0.05).The incidence of complications in the observation group was 2.56%,lower than 15.38% in the control group,and the difference was statistically significant (P < 0.05).Conclusion CAS with short operation time,the trauma is small,it can quickly clear the carotid artery,increasing blood oxygen in the brain,improve the cognitive function of the severe internal artery stenosis patients,has less complications.

关 键 词：颈动脉狭窄 颈动脉支架成形术 颈动脉内膜切除术 

分 类 号：R543[医药卫生—心血管疾病]