2018-2020年杭州市泌尿生殖道炎症患者生殖支原体感染调查  

Mycoplasma genitalium infections among patients with genitourinary tract inflammations in Hangzhou from 2018 to 2020

作　　者：李婷[1] 王昊泉[2] LI Ting;WANG Hao-quan(Clinical Laboratory,Zhejiang Provincial People's Hospital(Afiliated People's Hospital of Hangzhou Medical College)Laboratory Medicine Center,Hangzhou,Zhejiang310014,China;不详)

机构地区：[1]浙江省人民医院,杭州医学院附属人民医院检验医学中心临床检验科,浙江杭州310014 [2]杭州市第三人民医院检验科,浙江杭州310009

出　　处：《中国微生态学杂志》2022年第9期1088-1090,1093,共4页Chinese Journal of Microecology

摘　　要：目的检测泌尿生殖支原体(Mycoplasmagenitalium,MG)核酸以了解杭州地区泌尿生殖道炎症患者生殖支原体(MG)感染情况。方法采用实时荧光核酸恒温扩增技术(SAT)检测杭州市第三人民医院2018年1月至2020年12月共3901例疑似生殖泌尿道感染患者MG-RNA,同时也检测淋球菌(NG)、沙眼衣原体(CT)和解脲支原体(UU)。结果3901例患者中,共检测出MG-RNA阳性患者262例,阳性率为6.7%,其中男性MG阳性率为7.0%(237/3364),女性为4.7%25/537),两组差异具有统计学意义(P<0.05)。随着年龄的增大,阳性率越低。男性≤20岁组阳性率最高,为13.9%(16/115);女性≥60岁组无检出(0/52)。MG与UU合并感染率最高,女性感染率高于男性(P<0.01)。各年龄组MG阳性率差异有统计学意义(P<0.01)。结论杭州地区泌尿生殖道感染患者的MG感染率较高,男性MG感染率高于女性,不同年龄段男女MG感染情况并不相同,提示临床需重视该类疾病的MG检测。Objective To detect Mycoplasma genitalium(MG) nucleic acid to understand MG infections among patients with genitourinary tract inflammation living in Hangzhou City. Methods The RNAs of MG, Neisseria gonorrhoeae(NG),Chlamydia trachomatis(CT) and Ureaplasma urealyticum(UU) were detected in 3 091 patients with suspected genitourinary tract infections in The Third People’s Hospital of Hangzhou from January 2018 to December 2020 using simultaneous amplification and testing(SAT). Results The prevalence of MG infection was 6.7% among the 3 901 patients(262/3 901), and a higher prevalence was seen among men(7.0%, 237/3 364) than among women(4.7%, 25/537)(P<0.05). The prevalence of MG infections reduced with age. The highest positive rate of MG-RNA was seen in men at ages of 20 years and younger(13.9%, 16/115), and the lowest positive rate was detected among women at ages of 60 years and older(0, 0/52). The greatest co-infection rate was seen in MG and UU, and a higher prevalence rate was observed among women(P<0.01). In addition, there was an age-specific positive rate of MG-RNA among the subjects(P<0.01).Conclusion The detection rate of MG infection was high among patients with genitourinary tract infection living in Hangzhou City. The prevalence of MG infection is higher in men, and the prevalence of MG infection varied with age. Detection of MG infection is recommended in patients with genitourinary tract infection.

关 键 词：生殖支原体 泌尿生殖道感染 多重感染 实时荧光核酸恒温扩增检测技术 

分 类 号：R691.3[医药卫生—泌尿科学]