刘舟仙治疗瘄证用药规律研究  

Study on Administration Rules of LIU Zhouxian in Treating Epidemic Eruptive Disease

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作  者:鲁晏武 孟庆海 叶姝 张恋 叶静静[1] 陈宁刚 LU Yanwu;MENG Qinghai;YE Shu;ZHANG Lian;YE Jingjing;CHEN Ninggang

机构地区:[1]浙江中医药大学附属宁波市中医院,浙江宁波315000 [2]温州医科大学附属象山医院,浙江宁波315700

出  处:《新中医》2022年第19期20-24,共5页New Chinese Medicine

基  金:浙江省中医药科研基金项目(2021ZB252);宁波市中医医学重点学科建设项目(甬卫发[2021]96号2022-Z04)。

摘  要:目的:探讨民国名医刘舟仙治疗瘄证的组方用药规律。方法:收集《舟仙瘄述》中治瘄方剂,利用中医传承辅助平台(V2.5)统计刘氏治瘄的用药频次、性味归经及功效类别,利用关联规则、复杂系统熵聚类分析方法提取药物组合并演化新处方。结果:共筛选处方223首,涉及中药227味。高频药物有甘草、黄芩、牛蒡子等。治疗药物多以清热药、补虚药为主,药性以寒性居多,药味多以苦、甘为主,药物多归于肺、脾、胃经。常用药物组合有连翘-牛蒡子、黄芩-甘草等。复杂系统熵聚类分析衍化出核心药物组合16个,形成潜在新方8首。结论:刘舟仙治疗瘄证强调辛凉解表、清热解毒,在治疗过程中注重透邪和护阴存津,临床常采用消风散、化斑汤、中满分消汤等类方加减治疗。Objective: To discuss the prescription and administration rules of LIU Zhouxian a famous doctor of the Republic of China in the treatment of epidemic eruptive disease. Methods:Prescriptions for epidemic eruptive disease in Zhouxian Cushu were collected, Traditional Chinese Medicine Inheritance Support System V2.5 was used to sum up the frequency qi and flavor meridian entry and effect categories of medication in treating epidemic eruptive disease by LIU;methods of association rules and complex system entropy clustering analysis were used to extract medicine combinations and evolve new prescriptions.Results: A total of 223 prescriptions were screened involving 227 kinds of medicinals. High-frequency medicinals included Radix et Rhizoma Glycyrrhizae, Radix Scutellariae, Fructus Arctii and so on. Heatclearing medicinals and deficiency-supplementing medicinals took up the majority. The qi of the medicinals were mostly cold and the flavors were mainly bitter and sweet. The main meridian entries of the medicinals were the lung meridian the spleen meridian and the stomach meridian. Commonly-used medicinals combinations included Fructus Forsythiae-Fructus Arctii and Radix Scutellariae-Radix et Rhizoma Glycyrrhizae.Based on complex system entropy clustering analysis 16 core medicinals combinations were derived and 8new potential prescriptions were formed. Conclusion:In the treatment of epidemic eruptive disease LIU Zhouxian emphasized on clearing and releasing the exterior with pungent-cool medicinals venting pathogen and protecting yin to preserve fluids and the modified treatment with Xiaofeng powder Huaban tang Zhongman Fenxiao tang and other prescriptions was frequently used in clinical practice.

关 键 词:瘄证 用药规律 刘舟仙 中医传承辅助平台 护阴存津 

分 类 号:R254.3[医药卫生—中医内科学]

 

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