基于多指标综合评价炒桑白皮炮制工艺研究  

Research on Processing Technology of Fried Mulberry Bark Based on Comprehensive Evaluation of Multiple Indexes

作　　者：刘滢 董金香[1] 高原 杨辛欣[1] LIU Ying;DONG Jin-xiang;GAO Yuan;YANG Xin-xin(Key Laboratory of Active Ingredients in Traditional Chinese Medicine(TCM)Co-constructed by Jilin Province and Ministry of Education,Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学中药有效成分省部共建教育部重点实验室,吉林长春130117

出　　处：《时珍国医国药》2022年第9期2150-2153,共4页Lishizhen Medicine and Materia Medica Research

基　　金：吉林省重大科技专项(20200504005YY);吉林省科技发展计划项目(20200404091YY);吉林省科技发展计划项目(20160201001YY)。

摘　　要：目的建立桑白皮中桑皮苷A的含量测定方法,优选炒桑白皮前净制,软化,干燥方法,并优化桑白皮的炒制工艺。方法考察净制,软化及干燥过程对桑皮苷A含量及浸出物得率的影响,并采用正交试验和多指标综合加权评分法,以桑皮苷A含量,浸出物得率,色度值为评价指标,考察影响炒桑白皮炮制工艺的各个因素水平。结果净制,软化过程及干燥温度过高使桑皮苷A含量降低,故选用强水进行冲洗,大小分档闷润法进行软化,50℃温度下进行干燥。桑白皮的最佳炒制工艺为:炒制温度130℃,炒制时间40min,料器比1∶4。结论经优选的炒桑白皮炮制工艺稳定可行,为炒桑白皮的研究奠定基础。Objective To establish a method for the determination of Mulberroside A in Cortex Mori, optimize the purification, softening and drying methods before frying Cortex Mori, and optimize the frying process of Cortex Mori.Methods The effects of purification, softening and drying on the content of Mulberroside A and the yield of extract were investigated, and the orthogonal test and multi-index comprehensive weighted scoring method were used to evaluate the content of Mulberroside A, the yield of extract and chromaticity as the evaluation index. The levels of various factors affecting the processing technology of Cortex Mori were investigated. Results The net preparation, softening process and high drying temperature reduced the content of Mulberroside A, so strong water was selected for flushing, the softening method was used for softening, and the drying was carried out at 50 ℃. The best stir-frying technology of mulberry bark is as follows: the frying temperature is 130℃, the frying time is 40 min, and the ratio of material to material is 1∶4.Conclusion The optimized processing technology of fried Cortex Mori is stable and feasible, which lays a foundation for the study of fried Cortex Mori.

关 键 词：炒桑白皮 桑皮苷A 浸出物得率 色度 炮制工艺 

分 类 号：R283[医药卫生—中药学]