养心汤加减联合西药治疗小儿病毒性心肌炎恢复期临床研究  

Clinical Study on Modified Yangxin Tang Combined with Western Medicine for Children with Viral Myocarditis in Convalescence

作　　者：李祥[1] 李欣[1] 张莹莹[1] 张志强[1] LI Xiang;LI Xin;ZHANG Yingying;ZHANG Zhiqiang

机构地区：[1]河南中医药大学第三附属医院,河南郑州450003

出　　处：《新中医》2022年第20期119-122,共4页New Chinese Medicine

摘　　要：目的:观察养心汤加减联合西药治疗小儿病毒性心肌炎(VMC)恢复期的临床疗效及对患儿心功能的影响。方法:以随机数字表法将50例VMC患儿分为观察组与对照组各25例。对照组给予西药对症治疗,观察组在对照组基础上给予养心汤加减治疗,2组均连续治疗2周。评定2组临床疗效,比较2组治疗前后中医证候积分及心功能指标。结果:观察组总有效率88.00%,高于对照组64.00%(P<0.05)。治疗后,2组中医证候积分均较治疗前降低(P<0.05),观察组中医证候积分低于对照组(P<0.05)。治疗后,2组射血分数(EF)、心输出量(CO)、每搏输出量(SV)均较治疗前增大(P<0.05),观察组EF、SV、CO均大于对照组(P<0.05)。结论:养心汤加减联合西药治疗小儿VMC恢复期疗效确切,有助于缓解患儿的临床症状,改善心功能。Objective:To observe the clinical effect of modified Yangxin tang combined with western medicine on children with viral myocarditis(VMC)in convalescence and its effects on their heart function.Methods:A total of 50 cases of VMC children were assigned to the observation group and the control group by random number table method,with 25 cases in each group.The control group was treated with symptomatic treatment with western medicine,and the observation group was additionally treated with modified Yangxin tang based on the treatment of the control group.Both groups were continuously treated for two weeks.Clinical effects in the two groups were evaluated;Chinese medicine syndrome scores and heart function indexes were compared between the two groups.Results:The total effective rate was88.00%in the observation group,higher than that of 64.00%in the control group(P<0.05).After treatment,Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),and the score in the observation group was lower than that in the control group(P<0.05).After treatment,ejection fraction(EF),cardiac output(CO)and stroke volume(SV)in the two groups were increased when compared with those before treatment(P<0.05),and the three indexes in the observation group were larger than those in the control group(P<0.05).Conclusion:Modified Yangxin tang combined with western medicine has a definite curative effect in the treatment of VMC children in convalescence,which can help relieve their clinical symptoms and improve heart function.

关 键 词：小儿病毒性心肌炎 恢复期 养心汤 中医证候 心功能 

分 类 号：R725.4[医药卫生—儿科]