人参皂苷防治病理性瘢痕的研究进展  

Research Progress of Ginsenosides for the Prevention and Treatment of Pathological Scarring

作　　者：孔艳丽 皮龙泉 李初颖 金美彤 罗银利 金哲虎[1] KONG Yan-li;PI Long-quan;LI Chu-ying;JIN Mei-tong;LUO Yin-li;JIN Zhe-hu(Department of Dermatology,Affiliated Hospital of Yanbian University,Jilin Province,133000,China;Department of Medical Cosmetology,Affiliated Hospital of Yanbian University,Jilin Province,133000,China)

机构地区：[1]延边大学附属医院皮肤科,吉林延吉133000 [2]延边大学附属医院医学美容科,吉林延吉133000

出　　处：《中国医疗美容》2022年第11期75-78,共4页China Medical Cosmetology

基　　金：国家自然科学基金项目(81960561);国家自然科学基金项目(81760707)。

摘　　要：增生性瘢痕(hypertrophic scar,HS)和瘢痕疙瘩(Keloid,KD)是组织损伤后异常修复的结果。人参皂苷是人参中主要的活性成分,具有增强机体免疫力,改善心血管功能,抗炎,抗氧化和抗肿瘤等功能。病理性瘢痕作为一种类肿瘤的疾病,治疗方法众多,但因其病理机制尚不明确,导致现阶段的治疗手段较局限。该综述结合传统中药人参的药理学作用,探讨防治病理性瘢痕的最新研究进展。Hypertrophic scar(HS)and keloid(KD)are the result of abnormal repair of tissue damage.Ginsenosides are the main active ingredients in ginseng,which have the functions of enhancing immunity,improving cardiovascular function,anti-inflammatory,antioxidant and anti-tumor.Pathological scarring as a tumor-like disease has numerous therapeutic approaches,but its pathological mechanism is still unclear,resulting in limited therapeutic tools at this stage.This review discusses the latest research progress in the prevention and treatment of pathological scarring in the context of the pharmacological effects of the traditional Chinese medicine ginseng.

关 键 词：人参皂苷 增生性瘢痕 瘢痕疙瘩 

分 类 号：R285[医药卫生—中药学]