泽兰治疗PCOS排卵障碍之调经促孕理论及现代药理研究  

Study on the Theory of Regulating Menstruation and Promoting Pregnancy in the Treatment of PCOS Ovulation Disorder by Zelan(Lycopi Herba)and Its Modern Pharmacological Research

作　　者：李林珏 丁永芬[1] 李玲[1,2] LI Linjue;DING Yongfen;LI Ling(Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China;China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]中国中医科学院望京医院,北京100102 [2]中国中医科学院,北京100700

出　　处：《中医药导报》2022年第11期199-202,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：中国中医科学院科技创新工程重大攻关项目(CI2021A02417)。

摘　　要：对近年来泽兰治疗多囊卵巢综合征调经促孕作用及其相关药理作用机制进行统一论述。泽兰可通过活血利水调经、快气悦脾疏肝、补养气血等功效治疗多囊卵巢综合征排卵障碍引起的月经不调、不孕之症,具有良好临床疗效。泽兰现代药理作用主要为抗炎、抗氧化、改善微循环、降糖、降脂、保肝利胆、调节肠道菌群等,可针对多囊卵巢综合征排卵障碍慢性氧化应激、低度炎症状态、微循环障碍、胰岛素抵抗、肠道菌群紊乱等发病机制而起到治疗作用,为临床用药提供理论支持。In this paper,the effects of Zelan(Lycopi Herba)on regulating menstruation and promoting pregnancy in the treatment of polycystic ovary syndrome in recent years and its related pharmacological mechanisms were discussed.Zelan(Lycopi Herba)can regulate menstruation and promote pregnancy by invigorating blood and water,regulating menstruation,fasting qi,spleen and liver,nourishing qi and blood,and has a good clinical effect in the treatment of ovulation disorder in PCOS.The modern pharmacological effects of Zelan(Lycopi Herba)mainly include anti-inflammation,anti-oxidation,improvement of microcirculation,hypoglycemia,lipid-lowering,liver protection and cholagogic,regulation of intestinal flora,etc.It can play a therapeutic role in the pathogenesis of polycystic ovary syndrome ovulation disorder,chronic oxidative stress,low-grade inflammatory state,microcirculation disorder,insulin resistance,intestinal flora disorder,etc.,providing theoretical support for clinical medication.

关 键 词：多囊卵巢综合征 泽兰 排卵障碍 调经促孕 现代药理 研究进展 

分 类 号：R282.71[医药卫生—中药学]