倾向性评分匹配水囊引产在足月羊水偏少孕妇促宫颈成熟中的应用效果  

Study on application effects of water sac induced labor in promoting cervical maturation in pregnant women with term oligohydramnios:based propensity score matching

作　　者：矫洁[1] 黄春燕[1] 王均强 王锡梅[1] JIAO Jie;HUANG Chunyan;WANG Junqiang(Departmen t of Obstetrics and Gynecology,Affiliated Hospital of Jiangnan University,Jiangsu,Wuxi 214000,China;不详)

机构地区：[1]江南大学附属医院妇产科,江苏省无锡市214000 [2]武警第二机动总队医院

出　　处：《河北医药》2022年第20期3107-3109,3113,共4页Hebei Medical Journal

摘　　要：目的探究倾向性评分匹配(PSM)水囊引产在足月羊水偏少孕妇促宫颈成熟中的应用效果。方法回顾性分析2016年1月至2021年1月采用缩宫素引产的73例足月羊水偏少孕妇的临床资料纳入对照组,收集同期采用水囊引产联合缩宫素干预的41例足月羊水偏少孕妇的临床资料纳入观察组。运用PSM法(1∶2,卡钳值=0.01)基于孕妇年龄、孕周、体重指数等基线资料将对照组与观察组配对,匹配后对照组64例,观察组32例。比较2组治疗前、治疗12 h的宫颈成熟度Bishop评分;比较2组阴道分娩情况及母婴结局。结果治疗12 h,2组孕妇的宫颈Bishop评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组引产至活跃期、引产至分娩时间及总产程均短于对照组,差异有统计学意义(P<0.05)。2组新生儿窒息、羊水粪染、产后出血发生率比较,差异无统计学意义(P>0.05)。结论水囊引产可有效促进足月羊水偏少孕妇宫颈成熟,缩短分娩所需时间,且不增加不良母婴结局的发生率,安全性较好。Objective To explore the application effects of water sac-induced labor in promoting cervical maturation of pregnant women with term oligohydramnios by propensity score matching(PSM).Methods From January 2016 to January 2021,73 pregnant women with term oligohydramnios(control group)received labor induction of oxytocin-induced,41 synchronous pregnant women with term oligohydramnios(observation group)received labor induction of water sac-induced labor combined with oxytocin;The clinical data of these pregnant women were retrospectively analyzed.PSM method was applied(1∶2,caliper value=0.01)to match the control group with the observation group based on the baseline data involving the maternal age,gestational week and body mass index.There were 64 successful matching in the control group and 32 successful matching in the observation group.The Bishop scores of cervical maturity before and 12 hours after treatment between two groups were compared;and vaginal delivery and maternal and infant health outcomes between groups were compared.Results The Bishop scores of cervical maturity in both groups on hour 12 of post-treatment were higher than those before treatment,and the index of observation group was significantly higher compared with that of the control group(P<0.05).The duration from induced labor to active stage or from induced labor to delivery and total labor in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The difference in the incidence of neonatal asphyxia,meconium-stained amniotic fluid and postpartum hemorrhage between the two groups was no statistically significant(P>0.05).Conclusion For pregnant women with term oligohydramnios,Water sac-induced labor is effectively capable promoting cervical maturation and shortening delivery time,reducing adverse incidence,with high safety.

关 键 词：羊水偏少 足月 水囊引产 缩宫素 促宫颈成熟 母婴结局 

分 类 号：R714.2[医药卫生—妇产科学]