Baveno指标在门静脉高压出血风险筛查中的研究进展及其在晚期血吸虫病中的应用前景分析  

Research progress on Baveno index for the screening of risk of portal hypertensive bleeding and analysis on its application prospect in advanced schistosomiasis

作　　者：黄帅钦 侯循亚[2,3,4] 管洁 丁国建 陈鸿志[6] 邓维成 吴翔 HUANG Shuai-qin;HOU Xun-ya;GUAN Jie;DING Guo-jian;CHEN Hong-zhi;DENG Wei-cheng;WU Xiang(Department of Medical Parasitology,School of Basic Medical Science,Central South University,Changsha,Hunan 410013,China;Hunan Institute of Schistosomiasis Control,Yueyang,Hunan 414000,China;National Key Clinic of Schistosomiasis,Yueyang,Hunan 414000,China;Hunan Provincial Key Laboratory of Immunology and Transmission Control on Schistosomiasis,Yueyang,Hunan 414000,China;Department of Pathology,Hunan Aerospace Hospital,Changsha,Hunan 410006,China;The Second Xiangya Hospital of Central South University,Changsha,Hunan 410011,China)

机构地区：[1]中南大学基础医学院医学寄生虫学系,湖南长沙410013 [2]湖南省血吸虫病防治研究所,湖南岳阳414000 [3]国家血吸虫病临床重点专科,湖南岳阳414000 [4]血吸虫病免疫与传播控制湖南省重点实验室,湖南岳阳414000 [5]湖南航天医院病理科,湖南长沙410006 [6]中南大学湘雅二医院,湖南长沙410011

出　　处：《实用预防医学》2022年第11期1405-1408,F0003,共5页Practical Preventive Medicine

基　　金：2021年度湖南省卫生健康委科研计划项目(202104011369);中南大学科研启动经费(202044001)。

摘　　要：门静脉高压是危害中国700多万肝硬化病人临床预后的最主要原因,食管胃底静脉曲张破裂出血是其最常见的致死性并发症,所以建立与完善门静脉高压出血风险监测和管理制度,尤为迫切。Baveno共识是国际上最具权威的门静脉高压症临床诊断指南,其所提供的Baveno指标(肝静脉压力梯度、肝硬度测定值、血小板计数以及内镜检查)对门静脉高压和静脉曲张出血的筛查和检测都有着重要的临床指导意义。本研究通过对Baveno指标在门静脉高压出血风险筛查中的研究与应用进展进行综述,以期能够更好地了解各个指标的优缺点及目前该领域的研究现状,为优化、开发更加有效的筛查方法与指标提供参考,特别是为晚期血吸虫病人门静脉高压出血风险筛查提供依据。Portal hypertension is the main cause affecting the clinical prognoses of more than seven million cirrhotic patients in China, and rupture and bleeding from gastroesophageal varices is the most common fatal complication. Therefore, it is particularly urgent to establish and improve the risk screening and management system for portal hypertensive bleeding. Baveno consensus is the most authoritative international guideline for clinical diagnosis of portal hypertension, and Baveno index(including hepatic venous pressure gradient, liver hardness measurement, platelet count and endoscopy) based on Baveno consensus has important clinical guiding significance for the screening and detection of portal hypertension and gastroesophageal varices bleeding. This review summarizes the research and application progress on Baveno index for the screening of risk of portal hypertensive bleeding so as to better understand the strengths and weaknesses of all the indexes and the current research status in this field and provide references for optimizing and developing more effective screening methods and indexes, especially for the screening of risk of portal hypertension bleeding in patients with advanced schistosomiasis.

关 键 词：Baveno指标 门静脉高压 食管胃底静脉曲张 风险筛查 晚期血吸虫病 

分 类 号：R532.21[医药卫生—内科学]