多模态MRI在脑胶质瘤术前鉴别诊断中的应用价值分析  

Application Value of Multi-modal MRI in Preoperative Differential Diagnosis of Glioma

作　　者：侯振华[1] HOU Zhen-hua(Department of Radiology,Fuxin Central Hospital,Fuxin 123000,Liaoning Province,China)

机构地区：[1]阜新市中心医院放射科,辽宁阜新123000

出　　处：《中国CT和MRI杂志》2022年第12期24-26,共3页Chinese Journal of CT and MRI

摘　　要：目的探讨脑胶质瘤多模态磁共振成像(MRI)术前鉴别诊断价值。方法回顾性分析本院2017年2月至2019年9月本院55例手术及病理学证实为脑胶质瘤的患者临床资料,其中低级别27例,高级别28例,所有患者均先后通过多模态MRI检测,分析其在疾病术前鉴别中的应用价值。结果低级别、高级别组病变区域多分别表现为低灌注、高灌注,高级别组TBF、rTBF值高于低级别组(P<0.05);高级别胶质瘤肿瘤实质性部分的rMDt、rADt、rRDt、λ1t、λ2t、λ3t低于低级别组(P<0.05);MRI-ASL与MRIDTI扫描技术ROC联合诊断下AUC=0.944高于各参数TBF、rTBF、rMDt、rADt、rRDt、λ1t、λ2t、λ3tROC诊断下AUC=0.771、0.770、0.778、0.758、0.767、0.685、0.778、0.788(P<0.05);低级别组中DTT表现推移10例,浸润14例,破坏3例;高级别组DTT表现推移0例,浸润17例,破坏11例,胶质瘤级别越高,纤维束侵润越严重,低级别与高级别胶质瘤纤维束形态比较差异有统计学意义(P<0.05)。结论多模态MRI是脑胶质瘤诊断及分级评估的有效检测技术。Objective To explore the value of multi-modal magnetic resonance imaging(MRI)in preoperative differential diagnosis of glioma.Methods A retrospective analysis was performed on clinical data of 55 patients confirmed with glioma by surgery and pathology in the hospital between February 2017 and September 2019,including 27 cases in low-level group and 28 cases in high-level group.All underwent multi-modal MRI examination,and its value in preoperative differential diagnosis of glioma was analyzed.Results There was low perfusion and high perfusion of lesion areas in low-level group and high-level group,respectively.TBF and rTBF values in high-level group were higher than those in low-level group(P<0.05).The rMDt,rADt,rRDt,λ1t,λ2t andλ3t of tumor substantial part in high-level group were lower than those in low-level group(P<0.05).AUC of MRI-ASL combined with MRI-DTI was greater than that of TBF,rTBF,rMDt,rADt,rRDt,λ1t,λ2t andλ3t(0.944 vs 0.771,0.770,0.778,0.758,0.767,0.685,0.778,0.788)(P<0.05).In low-level group,there were 10 cases with DTT displacement,14 cases with infiltration and 3 cases with destruction.In high-level group,there was 0 case with DTT displacement,17 cases with infiltration and 11 cases with destruction.The higher the glioma level,the more severe the fiber bundle invasion.There was no significant difference in fiber bundle morphology between low-level and high-level glioma(P<0.05).Conclusion Multi-modal MRI is an effective detection technique in the diagnosis and grading evaluation of glioma.

关 键 词：脑胶质瘤 多模态磁共振成像 鉴别诊断 应用价值 

分 类 号：R445.2[医药卫生—影像医学与核医学]