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作 者:李姣姣 郑深根 苏展鹏 LI Jiaojiao;ZHENG Shengen;SU Zhanpeng(Department of Neonatology,Shenzhen Far East Obstetrics and Gynecology Hospital,Guangdong Province,Shenzhen,518000,China)
机构地区:[1]深圳远东妇产医院新生儿科,广东深圳518000
出 处:《中国当代医药》2022年第33期80-83,共4页China Modern Medicine
基 金:广东省深圳市罗湖区软科学研究计划项目(LX20200602)。
摘 要:目的探讨脐动脉血气分析(UABG)在足月小样儿中的应用效果。方法选取深圳远东妇产医院2019年8月至2020年8月出生的60例足月小样儿作为研究组,另选同期60名足月正常体重新生儿作为对照组,比较两组新生儿的脐动脉血气分析结果、生长发育、神经发育情况。研究组中出生时出现缺氧、窒息的27例患儿作为窒息组,另33例未发生缺氧、窒息的患儿作为正常组,比较两组的脐动脉血气分析结果。结果研究组的血液pH值、剩余碱(BE)低于对照组,动脉血二氧化碳分压(PaCO_(2))高于对照组,差异有统计学意义(P<0.05),两组新生儿的动脉血氧分压(PaO_(2))、碳酸氢根(HCO_(3)^(-))比较,差异无统计学意义(P>0.05)。窒息组患儿的pH值低于正常组,差异有统计学意义(P<0.05),而窒息组患儿的PaO_(2)、PaCO_(2)、HCO_(3)^(-)、BE与正常组比较,差异无统计学意义(P>0.05)。研究组的身高、体重低于对照组,生长发育迟缓率及消瘦率高于对照组,差异有统计学意义(P<0.05);研究组的神经发育水平、大运动、精细动作评分低于对照组,差异有统计学意义(P<0.05),两组的适应性评分比较,差异无统计学意义(P>0.05)。结论足月小样儿中往往出现生长发育和神经发育迟缓且伴随脐动脉血气分析相关指标异常。Objective To investigate the effect of umbilical artery blood gas analysis(UABG)in term infants.Methods A total of 60 full-term small infants born in Shenzhen Far East Obstetrics and Gynecology Hospital from August 2019 to August 2020 were selected as the study group,and another 60 full-term normal weight newborns in the same period were selected as the control group.The results of umbilical artery blood gas analysis,growth and nerve development were compared between the two groups.In the study group,27 children with hypoxia or asphyxia at birth were selected as the asphyxia group,and 33 children without hypoxia or asphyxia were selected as the normal group.The results of umbilical artery blood gas analysis were compared between the two groups.Results The blood pH value and residual base(BE)of the study group were lower than those of the control group,and the arterial partial pressure of carbon dioxide(PaCO_(2))was higher than that of the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the arterial partial pressure of oxygen(PaO_(2))and bicarbonate(HCO_(3)^(-))between the two groups(P>0.05).The pH value of the asphyxia group was lower than that of the normal group,and the difference was statistically significant(P<0.05),while the PaO_(2),PaCO_(2),HCO_(3)^(-)and BE of the asphyxia group were not significantly different from those of the normal group(P>0.05).The height and weight of the study group were lower than those of the control group,and the growth retardation rate and wasting rate of the study group were higher than those of the control group,and the differences were statistically significant(P<0.05).The neurodevelopmental level,gross motor and fine motor scores of the study group were lower than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the adaptability score between the two groups(P>0.05).Conclusion Growth and neurodevelopmental retardation accompanied by abn
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