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作 者:季加孚[1] 季科[1] JI Jia-fu;JI Ke(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Gastrointestinal Cancer Center,Peking University Cancer Hospital&Institute,Beijing 100142,China)
机构地区:[1]北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142
出 处:《中国实用外科杂志》2022年第10期1081-1083,1091,共4页Chinese Journal of Practical Surgery
基 金:国家自然科学基金联合基金重点项目(No.U20A20371)。
摘 要:近10年,随着我国胃癌早期诊断比例增高、规范化诊疗水平提升以及多项高质量的临床研究结果发布,胃癌治疗模式发生了改变,整体预后得到改善。临床研究的热点主要聚焦于手术方式的改变和发展,其中最活跃的是腹腔镜技术。在CLASS系列研究成果的推动下,我国腹腔镜胃癌手术开展例数呈现明显的上升趋势。围手术期化疗在进展期胃癌治疗中的地位已得到肯定,同时随着免疫治疗相关研究的重大突破,晚期胃癌病人也得到了前所未有的获益。个体化、精细化的治疗模式是我国胃癌诊治的特色,也是未来发展的趋势。In the past 10 years, treatment strategies for gastric cancer have developed,and helped to improve the overall prognosis of gastric cancer patients. The hotspot issue of clinical research mainly focus on the development of operative approaches, and the most active fields are related to laparoscopic technique. Driven by the research findings of CLASS series, laparoscopic gastrectomy quantity for gastric cancer performed in China has shown a significant upward trend. The clinical position of perioperative chemotherapy in the treatment of progressive gastric cancer has been affirmed,while patients with advanced gastric cancer have also received unprecedented benefits with the major breakthroughs in immunotherapy of gastric cancer. The individualized and refinement therapeutic modality is the characteristic of diagnosis and treatment of gastric cancer in China, and it is also the future.
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