姜状三七根茎的皂苷类化学成分研究  

Saponins from Rhizomes of Panax zingiberensis

作　　者：李晓波[1,2] 张高菊 张广辉[1,2] 杨生超 姜薇薇[1,2,3] LI Xiaobo;ZHANG Gaoju;ZHANG Guanghui;YANG Shengchao;JIANG Weiwei(Key Laboratory of Medicinal Plant Biology of Yunnan Province,Yunnan Agricultural University,Kunming 650201,China;National&Local Joint Engineering Research Center on Germplasms Utilization&Innovation of Chinese Medicinal Materials in Southwest China,Yunnan Agricultural University,Kunming 650201,China;College of Science,Yunnan Agricultural University,Kunming 650201,China)

机构地区：[1]云南农业大学,云南省药用植物生物学重点实验室,昆明650201 [2]云南农业大学,西南中药材种质创新与利用国家地方联合工程研究中心,昆明650201 [3]云南农业大学,理学院,昆明650201

出　　处：《热带亚热带植物学报》2022年第6期884-889,共6页Journal of Tropical and Subtropical Botany

基　　金：云南省基础研究计划面上项目(202201AT070266)资助。

摘　　要：为了解姜状三七(Panax zingiberensis)根茎的皂苷类化学成分,采用正相硅胶、反相硅胶和凝胶等色谱方法从其根茎的乙醇提取物中得到9个皂苷类化合物,根据理化性质和波谱数据,其结构分别鉴定为人参皂苷SL_(1)(1)、人参皂苷Rh_(1)(2)、三七皂苷R_(8)(3)、竹节参皂苷Ⅳa(4)、越南人参皂苷R_(10)(5)、人参皂苷Rg_(1)(6)、菠菜皂苷A 28-O-β-D-葡萄糖苷(7)、齐墩果酸28-O-β-D-葡萄糖苷(8)和姜状三七苷R_(1)(9)。化合物1、3、5、7和8为首次从该植物中分离得到,其中化合物5为奥克梯隆醇型皂苷,此类皂苷在该植物中未见报道。To investigate the chemical constituents from rhizomes of Panax zingiberensis,nine compounds were isolated and purified by methods of column chromatography on silica gel and Sephadex LH-20.Based on physical and chemical properties and spectral data,their structures were identified as ginsenoside SL_(1)(1),ginsenoside Rh_(1)(2),notoginsenoside R_(8)(3),chikusetsusaponin Ⅳa(4),vina-ginsenoside 10(5),ginsenoside Rg_(1)(6),spinasaponin A 28-O-β-D-glucopyranoside(7),oleanolic acid 28-O-β-D-glucopyranoside(8)and zingbroside R_(1)(9).Compounds 1,3,5,7,and 8 were isolated from P.zingiberensis for the first time.Compound 5 belongs to the ocotillol-type saponin,which was not previously reported from this species.

关 键 词：五加科 姜状三七 根茎 皂苷类 

分 类 号：R284.1[医药卫生—中药学]