320排容积CT分析原发性高血压患者升主动脉不同节段弹性特点  

Analysis of the elasticity of different segmental of ascending aortic in primary hypertension by 320 row volume CT

作　　者：梁占东[1] 刘彦芳 张晓辰 杨飞[1] 朱晓龙[1] 耿鹤群[1] 王晓灿 朱月香[1] 崔书君[1] LIANG Zhandong;LIU Yanfang;ZHANG Xiaochen;YANG Fei;ZHU Xiaolong;GENG Hequn;WANG Xiaocan;ZHU Yuexiang;CUI Shujun(Department of Medical Imaging,the First Affiliated Hospital of Hebei North University,Zhangjiakou,Hebei Province 075000,China)

机构地区：[1]河北北方学院附属第一医院医学影像部,河北张家口075000

出　　处：《实用放射学杂志》2022年第10期1603-1607,共5页Journal of Practical Radiology

基　　金：河北省医学科学研究重点课题计划项目(20180862)。

摘　　要：目的分析原发性高血压患者升主动脉不同节段的弹性特点。方法选取临床确诊为原发性高血压并行冠状动脉CT血管成像(CTA)检查的患者180例,同时选取60例正常血压者为对照组。测量并计算升主动脉不同节段的动脉弹性参数。分析升主动脉不同节段的弹性特点及升主动脉不同节段弹性参数与血压的关系。结果对照组升主动脉远心段动脉顺应性(AaC)值[(3.31±0.54)mm^(2)/mmHg]>管窦交界处AaC值[(2.85±0.48)mm^(2)/mmHg]>瓣环处A_(a)C值[(2.44±0.35)mm^(2)/mmHg],且差异有统计学意义;升主动脉远心段动脉可扩张度(AaD)值[(3.45±0.33)×10^(3) mmHg-1]<管窦交界处A_(a)D值[(4.17±0.59)×10^(3) mmHg^(-1)]<瓣环处AaD值[(6.30±0.61)×10^(3) mmHg-1],且差异有统计学意义。高血压组升主动脉瓣环层面、管窦交界层面及远心段AaD、AaC值均低于对照组(P<0.001),β_(a)值均明显高于对照组(P<0.001),并且收缩压与升主动脉不同节段AaD、AaC值均呈显著负相关,舒张压与升主动脉不同节段A_(a)D、A_(a)C值均呈负相关;收缩压、舒张压与升主动脉不同节段β_(a)值呈正相关。升主动脉不同节段A_(a)C值随收缩压升高而下降程度大致相同;升主动脉远心段AaD值下降的趋势快于瓣环处及管窦交界处;升主动脉远心段β_(a)值上升趋势也快于瓣环处及管窦交界处。结论升主动脉不同节段管腔弹性随着血压的升高而下降,高血压对升主动脉不同节段管腔的弹性影响趋势是相同的;升主动脉弹性随血压升高而下降程度存在区域性差异。ObjectiveTo investigate the elastic characteristics of different ascending aortic segments in patients with primary hypertension.Methods A total of 180 patients with primary hypertension who underwent coronary computed tomography angiography(CTA)were collected.6o patients with normal blood pressure were collected as the control group.Arterial elasticity parameters of different segments of the ascending aortic were measured and calculated.The elasticity characteristics of the different segments of the ascending aortic were analyzed,and the relationship between the elasticity parameters of the different segments of the ascending aortic and blood pressure was also analyzed.Results In the control group,the value of artery compliance(AaC)in the distal segment of the ascending aortic[(3.31±0.54)mm^(2)/mmHg]>at the junction of sinus[(2.85±0.48)mm^(2)/mmHg]>at the annulus[(2.44±0.35)mm^(2)/mmHg],and the difference was statistically significant.The value of artery distensibility(A_(a)D)in the distal segment of the ascending aortic[(3.45±0.33)×10^(3) mmHg^(-1)]<at the junction of sinus[(4.17±0.59)×10^(3) mmHg^(-1)]<at the annulus[(6.30±0.61)×10^(3) mmHg^(-1)],and the difference was statistically significant.The A.C and A.D values of the ascending aortic annulus,sinus junction,and distal segment in each hypertension group were lower than those in the control group(P<0.001).The values ofβa were significantly higher than those in the control group(P<0.oo1).There was a significant negative correlation between systolic blood pressure and the values of A_(a)D and A_(a)C in different segments of the ascending aortic,and there was a negative correlation between diastolic blood pressure and the values of A_(a)D and A_(a)C in different segments of the ascending aortic,Systolic blood pressure,diastolic blood pressure and different segments of the ascending aortic β_(a) value were positively correlated.The A_(a)D value of the different segments of the ascending aortic decreased with the increase of systolic blood pressure.T

关 键 词：原发性高血压 升主动脉 动脉弹性 计算机体层成像 

分 类 号：R544.1+1[医药卫生—心血管疾病] R543.1[医药卫生—内科学] R814.42[医药卫生—临床医学]