Influence of herbal cake-partitioned moxibustion on lumbar functions and inflammatory factors in patients with lumbar disc herniation due to kidney deficiency and blood stasis  

隔药饼灸对肾虚血瘀腰椎间盘突出症腰椎功能及炎症因子的影响

作　　者：BI Dingyan LI Hongliang HE Dao CAO Jianan OUYANG Lizhi LIU Huijuan WANG Jing YI Zhan ZHANG Kaiwei 贲定严;李洪亮;何道;曹佳男;欧阳里知;刘惠娟;王晶;易展;张凯维(Hunan University of Chinese Medicine,Changsha 410208,China;The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China;Yueyang Hospital of Traditional Chinese Medicine,Yueyang 414000,China;不详)

机构地区：[1]Hunan University of Chinese Medicine,Changsha 410208,China [2]The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China [3]Yueyang Hospital of Traditional Chinese Medicine,Yueyang 414000,China [4]不详

出　　处：《Journal of Acupuncture and Tuina Science》2022年第5期370-375,共6页针灸推拿医学（英文版）

基　　金：湖南省自然科学基金项目,No.2021JJ40396;湖南省教育厅科学研究项目,No.19C1397。

摘　　要：Objective To observe the efficacy of herbal cake-partitioned moxibustion for lumbar disc herniation(LDH)due to kidney deficiency and blood stasis and observe the influence of this method on lumbar functions and inflammatory factors in patients with this condition.Methods A total of 120 LDH patients who met the inclusion criteria were randomly divided into three groups,including a herbal cake-partitioned moxibustion group,a flour cake-partitioned moxibustion group,and a Western medication group,with 40 patients in each group.The patients in the Western medication group were treated with diflunisal tablets,0.5 g per dose,2 doses a day.Those in the herbal cake-partitioned moxibustion group were treated with additional herbal cake-partitioned moxibustion group at Back-Shu Points and Jiaji(EX-B2)Points once a day.Those in the flour cake-partitioned moxibustion group were treated with the same methods as in the herbal cake-partitioned moxibustion group,except that the herbal cake was replaced by a flour cake.All the patients were treated for 10 d.After treatment,the scores of the visual analog scale(VAS)and Japanese Orthopaedic Association(JOA)and the changes of the interleukin(IL)-6,tumor necrosis factor(TNF)-α,and substance P(SP)levels were observed,and the efficacy was evaluated.Results After treatment,the VAS score and the levels of IL-6,TNF-α,and SP were lower than those before treatment,and the JOA score was higher than that before treatment in the three groups,indicating intra-group statistical significance(P<0.05).The VAS score and the levels of IL-6,TNF-α,and SP of the herbal cake-partitioned moxibustion group were lower than those of the flour cake-partitioned moxibustion group and the Western medication group,while the JOA score of the herbal cake-partitioned moxibustion group was higher than that of the other two groups,indicating inter-group statistical significance(P<0.05).The total effective rate of the herbal cake-partitioned moxibustion group was 92.5%,higher than that of the flour cake-partitioned 目的观察隔药饼灸治疗肾虚血瘀腰椎间盘突出症(LDH)的临床疗效及其对腰椎功能和炎症因子的影响.方法将120例符合纳入标准的LDH患者按随机数字表法分为隔药饼灸组、隔面饼灸组和西药组,每组40例.西药组予口服二氟尼柳片,0.5 g/次,2次/d.隔药饼灸组在此基础上加用隔药饼灸背俞穴和夹脊穴,1次/d.隔面饼灸组操作同隔药饼灸组,仅将药饼换成面饼.三组均治疗10 d.治疗后观察视觉模拟量表(VAS)评分、日本骨科协会(JOA)评分及血清白介素(IL)-6、肿瘤坏死因子(TNF)-α及P物质水平变化,并评价临床疗效.结果治疗后,三组患者VAS评分,血清IL-6、TNF-α及P物质水平均较本组治疗前下降,JOA评分均较本组治疗前升高,组内差异均有统计学意义(P<0.05).隔药饼灸组VAS评分及血清IL-6、TNF-α及P物质水平低于隔面饼灸组及西药组,而JOA评分高于隔面饼灸组及西药组,组间差异均有统计学意义(P<0.05).隔药饼灸组的总有效率为92.5%,高于隔面饼灸组的80.0%和西药组的72.5%,组间差异均有统计学意义(P<0.05).结论在口服西药基础上加用隔药饼灸能减轻肾虚血瘀LDH患者疼痛,改善腰椎功能,疗效优于隔面饼灸和单独西药治疗,其作用机制可能与降低血清炎症因子水平有关.

关 键 词：Moxibustion Therapy Indirect Moxibustion Medicinal Cake-partitioned Moxibustion Inflammatory Factors Pain Measurement Intervertebral Disc Displacement Low Back Pain 

分 类 号：R245.8[医药卫生—针灸推拿学]